5-Bromo-4-chloro-2-methoxymethoxy-benzoic acid methoxymethyl ester

Base Information

• Chemical Name: 5-Bromo-4-chloro-2-methoxymethoxy-benzoic acid methoxymethyl ester
• CAS No.: 1027934-91-3
• Molecular Formula: C₁₁H₁₂BrClO₅
• Molecular Weight: 339.57
• Mol file: 1027934-91-3.mol

Synonyms:

Chemical Property of 5-Bromo-4-chloro-2-methoxymethoxy-benzoic acid methoxymethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Bromo-4-chloro-2-methoxymethoxy-benzoic acid methoxymethyl ester

There total 1 articles about 5-Bromo-4-chloro-2-methoxymethoxy-benzoic acid methoxymethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloromethyl methyl ether (107-30-2) + 5-bromo-4-chloro-2-hydroxybenzoic acid (142167-38-2) → 5-Bromo-4-chloro-2-methoxymethoxy-benzoic acid methoxymethyl ester (1027934-91-3)

Guidance literature:

With potassium carbonate; In acetone; for 5h; Ambient temperature;

DOI:10.1248/cpb.45.1994

Reference yield:

5-Bromo-4-chloro-2-methoxymethoxy-benzoic acid methoxymethyl ester (1027934-91-3) → 5-bromo-4-chloro-2-methoxymethoxybenzyl alcohol (162269-95-6)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 0.5h; Yield given; Ambient temperature;

DOI:10.1248/cpb.45.1994

Reference yield:

5-Bromo-4-chloro-2-methoxymethoxy-benzoic acid methoxymethyl ester (1027934-91-3) → 5-bromo-4-chloro-2-methoxymethoxybenzyl cyanide (162269-96-7)

Guidance literature:

Multi-step reaction with 3 steps

1: LiAlH₄ / diethyl ether / 0.5 h / Ambient temperature

2: Et₃N / CH₂Cl₂ / 5 h / Ambient temperature

3: sodium iodide / dimethylsulfoxide / 10 h / Ambient temperature

With lithium aluminium tetrahydride; triethylamine; sodium iodide; In diethyl ether; dichloromethane; dimethyl sulfoxide;

DOI:10.1248/cpb.45.1994

upstream raw materials:

chloromethyl methyl ether

5-bromo-4-chloro-2-hydroxybenzoic acid

Downstream raw materials:

5-bromo-4-chloro-2-methoxymethoxybenzyl alcohol

5-bromo-4-chloro-2-methoxymethoxybenzyl cyanide

2-(5-bromo-4-chloro-2-hydroxybenzoyl)-3-hydroxypyridine

(5-Bromo-4-chloro-2-hydroxy-phenyl)-(3-hydroxy-pyridin-2-yl)-methanone O-tert-butyl-oxime

Refernces