Technology Process of 1-methyl-5-indole
There total 8 articles about 1-methyl-5-indole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
manganese(IV) oxide;
In
benzene;
for 3h;
Ambient temperature;
DOI:10.1007/BF00472745
- Guidance literature:
-
Multi-step reaction with 4 steps
1: petroleum ether; tetrahydrofuran / 2 h / -10 °C
2: 84 percent / BBr3 / CH2Cl2 / 1 h
3: 86 percent / pyridine / 0.5 h / Heating
4: MnO2 / benzene / 3 h / Ambient temperature
With
pyridine; manganese(IV) oxide; boron tribromide;
In
tetrahydrofuran; dichloromethane; Petroleum ether; benzene;
DOI:10.1007/BF00472745
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 2) sulfosalicylic acid / 1) THF, Et2O, 15 min at 0 deg C, then 15 min at 20 deg C; 2) benzene, reflux
2: 84 percent / BBr3 / CH2Cl2 / 1 h
3: 86 percent / pyridine / 0.5 h / Heating
4: MnO2 / benzene / 3 h / Ambient temperature
With
pyridine; manganese(IV) oxide; boron tribromide; 5-sulfosalicylic Acid;
In
dichloromethane; benzene;
DOI:10.1007/BF00472745