2-Naphthalenecarboxylic acid, 1,1-dimethylethyl ester

Base Information

• Chemical Name: 2-Naphthalenecarboxylic acid, 1,1-dimethylethyl ester
• CAS No.: 115298-62-9
• Molecular Formula: C15H16O2
• Molecular Weight: 228.291
• Mol file: 115298-62-9.mol

Synonyms:

Chemical Property of 2-Naphthalenecarboxylic acid, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Naphthalenecarboxylic acid, 1,1-dimethylethyl ester

There total 1 articles about 2-Naphthalenecarboxylic acid, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl naphthalene-2-carboxylate (2459-25-8) + potassium tert-butylate (865-47-4) → 2-Naphthalenemethanol (1592-38-7) + 2-naphthoic acid tert-butyl ester (115298-62-9) + naphthalene-2-carboxylate (93-09-4)

Guidance literature:

With [RuCl₂(N-heterocyclic carbene)(bis[2-(diphenylphosphino)ethyl]amine)]; hydrogen; In 2-methyltetrahydrofuran; at 30 ℃; for 6h; under 6000.6 Torr; Pressure; Temperature; Catalytic behavior; Autoclave;

DOI:10.1021/acs.oprd.0c00410

Reference yield: 72.0%

2-naphthoic acid tert-butyl ester (115298-62-9) → 2-Methylnaphthalene (91-57-6,34468-07-0)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; 1,1,3,3-Tetramethyldisiloxane; potassium tert-butylate; 1,3-bis(cyclohexyl)imidazolium tetrafluoroborate; In toluene; at 110 ℃; for 10h; Glovebox; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.0c02405

Reference yield: 70.0%

2-naphthoic acid tert-butyl ester (115298-62-9) → 2-naphthaloyl chloride (2243-83-6)

Guidance literature:

With phosphorus trichloride; In acetonitrile; at 80 ℃; for 3h; Schlenk technique;

DOI:10.1177/1747519819898142

upstream raw materials:

methyl naphthalene-2-carboxylate

potassium tert-butylate

Downstream raw materials:

(2,5-dimethylphenyl)naphthalen-2-ylmethanone

2-Methylnaphthalene

2-naphthaloyl chloride

Refernces