14-phenyl-benz[5,6]indolo[2,1-a]isoquinoline-8,13-dione

Base Information

• Chemical Name: 14-phenyl-benz[5,6]indolo[2,1-a]isoquinoline-8,13-dione
• CAS No.: 121677-51-8
• Molecular Formula: C₂₆H₁₅NO₂
• Molecular Weight: 373.411
• Mol file: 121677-51-8.mol

Synonyms:

Chemical Property of 14-phenyl-benz[5,6]indolo[2,1-a]isoquinoline-8,13-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 14-phenyl-benz[5,6]indolo[2,1-a]isoquinoline-8,13-dione

There total 3 articles about 14-phenyl-benz[5,6]indolo[2,1-a]isoquinoline-8,13-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-dihydroisoquinoline (3230-65-7) → 14-phenyl-benz[5,6]indolo[2,1-a]isoquinoline-8,13-dione (121677-51-8)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium / 190 °C

2: ethanol

With ethanol; palladium;

DOI:10.1021/ja01562a048

Reference yield:

N-(2-phenylethyl)formamide (23069-99-0) → 14-phenyl-benz[5,6]indolo[2,1-a]isoquinoline-8,13-dione (121677-51-8)

Guidance literature:

Multi-step reaction with 3 steps

1: polyphosphoric acid / 200 °C

2: palladium / 190 °C

3: ethanol

With PPA; ethanol; palladium;

DOI:10.1021/ja01562a048

Reference yield:

2,3-Dichloro-1,4-naphthoquinone (117-80-6) + isoquinoline (119-65-3) + 1-phenyl-acetone (103-79-7,136675-26-8) → 14-phenyl-benz[5,6]indolo[2,1-a]isoquinoline-8,13-dione (121677-51-8) + 2-oxy-3-(isoquinolinium-2'-yl)-1,4-naphthoquinone (1236-39-1)

Guidance literature:

With ethanol;

DOI:10.1021/ja01562a048

upstream raw materials:

2,3-Dichloro-1,4-naphthoquinone

isoquinoline

1-phenyl-acetone

3,4-dihydroisoquinoline

Downstream raw materials:

8,13-diacetoxy-14-phenyl-benz[5,6]indolo[2,1-a]isoquinoline