3-Methyl-1,3-butanediaMine

Base Information

• Chemical Name: 3-Methyl-1,3-butanediaMine
• CAS No.: 116473-67-7
• Molecular Formula: C5H14N2
• Molecular Weight: 102.17800
• Mol file: 116473-67-7.mol

Synonyms:1,3-Butanediamine,3-methyl;

Chemical Property of 3-Methyl-1,3-butanediaMine

Chemical Property:

• PSA: 52.04000
• LogP: 1.47310

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methyl-1,3-butanediaMine

There total 1 articles about 3-Methyl-1,3-butanediaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N,N,dimethyl-1,3-propanediamine (116473-67-7)

Guidance literature:

Reference yield:

N,N,dimethyl-1,3-propanediamine (116473-67-7) → 1-[(2S)-2-hydroxy-2-phenylethyl]-2,2-dimethyl-8-morpholino-3,4-dihydropyrimido[1,2-a]pyrimidin-6-one

Guidance literature:

Multi-step reaction with 5 steps

1: acetonitrile / 2.5 h / Reflux

2: sodium methylate / methanol / 3 h

3: trichlorophosphate / 1,2-dichloro-ethane / 2 h / 65 °C

4: caesium carbonate / acetonitrile / 24 h / 80 °C

5: 50 °C

With sodium methylate; caesium carbonate; trichlorophosphate; In methanol; 1,2-dichloro-ethane; acetonitrile;

DOI:10.1021/jm5013352

Reference yield:

N,N,dimethyl-1,3-propanediamine (116473-67-7) → 8-chloro-1-[(2S)-2-hydroxy-2-phenylethyl]-2,2-dimethyl-3,4-dihydropyrimido[1,2-a]pyrimidin-6-one

Guidance literature:

Multi-step reaction with 4 steps

1: acetonitrile / 2.5 h / Reflux

2: sodium methylate / methanol / 3 h

3: trichlorophosphate / 1,2-dichloro-ethane / 2 h / 65 °C

4: caesium carbonate / acetonitrile / 24 h / 80 °C

With sodium methylate; caesium carbonate; trichlorophosphate; In methanol; 1,2-dichloro-ethane; acetonitrile;

DOI:10.1021/jm5013352

Refernces