1-Hexadecene, 16-bromo-

Base Information

• Chemical Name: 1-Hexadecene, 16-bromo-
• CAS No.: 118625-56-2
• Molecular Formula: C16H31Br
• Molecular Weight: 303.326
• Mol file: 118625-56-2.mol

Synonyms:16-Bromo-1-hexadecene;1-Hexadecene,16-bromo;

Chemical Property of 1-Hexadecene, 16-bromo-

Chemical Property:

• PSA: 0.00000
• LogP: 6.63860

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Hexadecene, 16-bromo-

There total 5 articles about 1-Hexadecene, 16-bromo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

1,11-dibromoundecane (16696-65-4) + bromopentene (1119-51-3) → ω-hexadecenyl bromide (118625-56-2)

Guidance literature:

bromopentene; With iodine; magnesium; In tetrahydrofuran; at 50 ℃; for 4h; Inert atmosphere;

1,11-dibromoundecane; With 1-methyl-pyrrolidin-2-one; dilithium tetrachlorocuprate(II); In tetrahydrofuran; at 0 - 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/cmdc.202100134

Reference yield:

1-bromo-4-butene (5162-44-7) + 1,12-dibromododecane (3344-70-5) → ω-hexadecenyl bromide (118625-56-2)

Guidance literature:

With magnesium; dilithium tetrachlorocuprate; Yield given. Multistep reaction; 1.) Et₂O, ref., 6.0 h; 2.) THF, Et₂O, from 0 deg C to r.t., 16 h;

DOI:10.1055/s-1995-4058

Reference yield:

10-Undecen-1-ol (112-43-6) → ω-hexadecenyl bromide (118625-56-2)

Guidance literature:

Multi-step reaction with 3 steps

2: LiBr

3: Mg, Li₂CuCl₄

With dilithium tetrachlorocuprate; magnesium; lithium bromide;

DOI:10.1016/S0040-4039(00)80820-5

upstream raw materials:

1,5-dibromo-pentane

1-undecen-11-ylbromide

1-bromo-4-butene

1,12-dibromododecane

Downstream raw materials:

trichloro-hexadecyl-silane

thioacetic acid S-(16-phenoxy-hexadecyl) ester

hexadec-15-enyloxy-benzene

15-hexadecenyltrichlorosilane

Refernces

• 1、 Kaplan, Anna R.,Schrank, Cassandra L.,Wuest, William M.. "An Efficient Synthesis of 3-Alkylpyridine Alkaloids Enables Their Biological Evaluation". . p. 2487 - 2490. Retrieved 2021.