2-Hydroxyquinoline-1(2h)-carbonitrile

Base Information

• Chemical Name: 2-Hydroxyquinoline-1(2h)-carbonitrile
• CAS No.: 941-87-7
• Molecular Formula: C10H8 N2 O
• Molecular Weight: 172.186
• European Community (EC) Number: 654-668-9
• NSC Number: 74479
• DSSTox Substance ID: DTXSID00291254
• Mol file: 941-87-7.mol

Synonyms:2-hydroxyquinoline-1(2h)-carbonitrile;941-87-7;2-hydroxy-2H-quinoline-1-carbonitrile;1-CYANO-1,2-DIHYDRO-2-HYDROXYQUINOLINE;NSC74479;SCHEMBL935561;DTXSID00291254;GXIXLQJBGXQENY-UHFFFAOYSA-N;NSC-74479;AKOS024332363;N-cyano-2-hydroxy-1,2-dihydroquinoline;1(2H)-Quinolinecarbonitrile, 2-hydroxy-

Chemical Property of 2-Hydroxyquinoline-1(2h)-carbonitrile

Chemical Property:

• Vapor Pressure: 3.49E-07mmHg at 25°C
• Boiling Point: 402°Cat760mmHg
• Flash Point: 196.9°C
• PSA: 47.26000
• Density: 1.33g/cm³
• LogP: 1.38428
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 172.063662883
• Heavy Atom Count: 13
• Complexity: 265

Purity/Quality:

99% ^*data from raw suppliers

1-Cyano-1,2-dihydro-2-hydroxyquinoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC(N2C#N)O

Technology Process of 2-Hydroxyquinoline-1(2h)-carbonitrile

There total 3 articles about 2-Hydroxyquinoline-1(2h)-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

quinoline (91-22-5) + bromocyane (506-68-3) → 2-hydroxy-2H-quinoline-1-carbonitrile (941-87-7)

Guidance literature:

With diethyl ether; at 0 ℃;

Reference yield:

quinoline (91-22-5) + bromocyane (506-68-3) → 2-hydroxy-2H-quinoline-1-carbonitrile (941-87-7)

Guidance literature:

With water;

Reference yield:

→ 2-hydroxy-2H-quinoline-1-carbonitrile (941-87-7)

Guidance literature:

Chinolin, 1) KCN, Br2, 2) wss. HCl;

upstream raw materials:

quinoline

bromocyane

Downstream raw materials:

cyanic acid

bromocyane

quinoline hydrochloride

cyanogen chloride