N-Formyl 2-chloro-5-(trifluoromethyl)aniline, N-[2-Chloro-5-(trifluoromethyl)phenyl]formamide

Base Information

• Chemical Name: N-Formyl 2-chloro-5-(trifluoromethyl)aniline, N-[2-Chloro-5-(trifluoromethyl)phenyl]formamide
• CAS No.: 657-63-6
• Molecular Formula: C₈H₅ClF₃NO
• Molecular Weight: 223.582
• Hs Code.: 2924299090
• Mol file: 657-63-6.mol

Synonyms:m-Formotoluidide,6'-chloro-a,a,a-trifluoro-(7CI,8CI); N-[2-Chloro-5-(trifluoromethyl)phenyl]formamide; NSC 50863

Chemical Property of N-Formyl 2-chloro-5-(trifluoromethyl)aniline, N-[2-Chloro-5-(trifluoromethyl)phenyl]formamide

Chemical Property:

• Vapor Pressure: 0.000564mmHg at 25°C
• Boiling Point: 311.4°C at 760 mmHg
• PKA: 13.52±0.70(Predicted)
• Flash Point: 142.1°C
• PSA: 29.10000
• Density: 1.474g/cm³
• LogP: 3.63600

Purity/Quality:

99% ^*data from raw suppliers

N-Formyl2-chloro-5-trifluoromethylaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Formyl 2-chloro-5-(trifluoromethyl)aniline, N-[2-Chloro-5-(trifluoromethyl)phenyl]formamide

There total 1 articles about N-Formyl 2-chloro-5-(trifluoromethyl)aniline, N-[2-Chloro-5-(trifluoromethyl)phenyl]formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6-Chlor-3-trifluormethyl-formanilid (657-63-6)

Guidance literature:

6-Chlor-3-trifluormethyl-anilin, Dimethylformamid i. Ggw. v. Natriummethylat;

DOI:10.1021/jo01351a623

Reference yield:

6-Chlor-3-trifluormethyl-formanilid (657-63-6) + dichlorofluoromethanesulphenyl chloride (2712-93-8) → C6H3Cl(CF3)N(CHO)SCFCl2 (74702-27-5)

Guidance literature:

In cyclohexane; in the presence of (C2H5)3N;

Reference yield:

6-Chlor-3-trifluormethyl-formanilid (657-63-6) → 2-chloro-5-trifluoromethylphenyl isocyanide dichloride (16001-46-0)

Guidance literature:

With thionyl chloride; sulfuryl dichloride;

Downstream raw materials:

2-chloro-5-trifluoromethylphenyl isocyanide dichloride

C₆H₃Cl(CF₃)N(CHO)SCFCl₂