anti-2'-benzyl-1,2,3,4-tetrahydronaphthalene-1-spiro-3'-oxaziridine

Base Information

• Chemical Name: anti-2'-benzyl-1,2,3,4-tetrahydronaphthalene-1-spiro-3'-oxaziridine
• CAS No.: 92885-62-6
• Molecular Formula: C₁₇H₁₇NO
• Molecular Weight: 251.328
• Mol file: 92885-62-6.mol

Synonyms:

Chemical Property of anti-2'-benzyl-1,2,3,4-tetrahydronaphthalene-1-spiro-3'-oxaziridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of anti-2'-benzyl-1,2,3,4-tetrahydronaphthalene-1-spiro-3'-oxaziridine

There total 5 articles about anti-2'-benzyl-1,2,3,4-tetrahydronaphthalene-1-spiro-3'-oxaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

→ anti-2'-benzyl-1,2,3,4-tetrahydronaphthalene-1-spiro-3'-oxaziridine (92885-62-6,92885-64-8,120530-13-4)

Guidance literature:

In toluene; for 1h; Heating;

DOI:10.1039/P19880003399

Reference yield:

1-benzylimino-1,2,3,4-tetrahydronaphthalene (32851-51-7,92885-60-4) → anti-2'-benzyl-1,2,3,4-tetrahydronaphthalene-1-spiro-3'-oxaziridine (92885-62-6,92885-64-8,120530-13-4)

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1039/P19880003399

Reference yield:

3,4-dihydronaphthalene-1(2H)-one (529-34-0) → anti-2'-benzyl-1,2,3,4-tetrahydronaphthalene-1-spiro-3'-oxaziridine (92885-62-6,92885-64-8,120530-13-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / toluene-p-sulphonic acid / benzene / 2 h / Heating

2: m-chloroperbenzoic acid, sodium hydrogen carbonate / CH₂Cl₂ / 2 h / 0 °C

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; toluene-4-sulfonic acid; In dichloromethane; benzene;

DOI:10.1039/P19880003399

upstream raw materials:

(E)-N-(3,4-dihydronaphthalene-1(2H)-ylidene)-1-phenylmethanamine

1-benzylimino-1,2,3,4-tetrahydronaphthalene

3,4-dihydronaphthalene-1(2H)-one

benzylamine

Downstream raw materials:

2-benzyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-one

N-benzyl-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one

3,4-dihydronaphthalene-1(2H)-one

Refernces

• 1、 Johnson, G. P.,Marples, B. A.. "PHOTOCHEMISTRY OF N-SUBSTITUTED SPIROOXAZIRIDINES DERIVED FROM TETRALONE-1". . p. 3359 - 3362. Retrieved 2007/10/02.