Technology Process of diethyl N-(N-benzyloxycarbonylisonipecotinoyl)-L-glutamate
There total 3 articles about diethyl N-(N-benzyloxycarbonylisonipecotinoyl)-L-glutamate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 83 percent / sodium bicarbonate; 6N HCl / H2O; diethyl ether / 4 h / Ambient temperature
2: 1) ethyl chloroformate, triethylamine; / 1) ethyl acetate, room temp.,1 h; 2) room temp., 2 h
With
hydrogenchloride; chloroformic acid ethyl ester; sodium hydrogencarbonate; triethylamine;
In
diethyl ether; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 83 percent / sodium bicarbonate; 6N HCl / H2O; diethyl ether / 4 h / Ambient temperature
2: 1) ethyl chloroformate, triethylamine; / 1) ethyl acetate, room temp.,1 h; 2) room temp., 2 h
With
hydrogenchloride; chloroformic acid ethyl ester; sodium hydrogencarbonate; triethylamine;
In
diethyl ether; water;
- Guidance literature:
-
With
chloroformic acid ethyl ester; triethylamine;
Yield given. Multistep reaction;
1) ethyl acetate, room temp.,1 h; 2) room temp., 2 h;
