4β,15-Diacetylnivalenol

Base Information

• Chemical Name: 4β,15-Diacetylnivalenol
• CAS No.: 6022-19-1
• Molecular Formula: C₁₉H₂₄O₉
• Molecular Weight: 396.394
• Mol file: 6022-19-1.mol

Synonyms:

Chemical Property of 4β,15-Diacetylnivalenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4β,15-Diacetylnivalenol

There total 2 articles about 4β,15-Diacetylnivalenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

4,15-diacetoxyscirpenol (2270-40-8,28776-47-8) → 4β,15-Diacetylnivalenol (6022-19-1,14287-82-2) + 4β,15-Diacetoxy-3α-hydroxy-12,13-epoxytrichothec-9-en-8-one (77620-47-4) + 4β,15-Diacetoxy-12,13-epoxy-3α-hydroxytrichothec-9-en-16-one (129839-73-2) + 4β,15-Diacetoxy-3α,8β-dihydroxy-12,13-epoxytrichothec-9-ene (77620-53-2)

Guidance literature:

With selenium(IV) oxide; In 1,4-dioxane; water; for 22h; Yield given; Heating;

Reference yield:

→ 4β,15-Diacetylnivalenol (6022-19-1,14287-82-2)

Guidance literature:

Triol III (R=H), MnO2;

DOI:10.1039/j39700000375

Reference yield:

4β,15-Diacetylnivalenol (6022-19-1,14287-82-2) → 3-hemisuccinylnivalenol (154027-29-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 mg / aq. Na₂CO₃ / methanol / 3 h / 23 °C

2: 1.) pyridine, n-butylboronic acid, 2.) DMAP / 1.) RT, overnight, 2.) RT, 4 h

With pyridine; dmap; butylboronic acid; sodium carbonate; In methanol;

DOI:10.1021/jf00039a046

upstream raw materials:

4,15-diacetoxyscirpenol

Downstream raw materials:

nivalenol

3-hemisuccinylnivalenol

3,4-dihemisuccinylnivalenol

Refernces