N′-methoxycarbonylhydrazone of 1-(diphenylphosphoryl)propan-2-one

Base Information

• Chemical Name: N′-methoxycarbonylhydrazone of 1-(diphenylphosphoryl)propan-2-one
• CAS No.: 103538-60-9
• Molecular Formula: C₁₇H₁₉N₂O₃P
• Molecular Weight: 330.323
• Mol file: 103538-60-9.mol

Synonyms:

Chemical Property of N′-methoxycarbonylhydrazone of 1-(diphenylphosphoryl)propan-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N′-methoxycarbonylhydrazone of 1-(diphenylphosphoryl)propan-2-one

There total 2 articles about N′-methoxycarbonylhydrazone of 1-(diphenylphosphoryl)propan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

hydrazinecarboxylic acid methyl ester (6294-89-9) + 1-(diphenylphosphinoyl)propan-2-one (1733-52-4) → N′-methoxycarbonylhydrazone of 1-(diphenylphosphoryl)propan-2-one (103518-03-2,103538-60-9)

Guidance literature:

With acetic acid; In methanol; at 20 ℃; for 6h; Reagent/catalyst;

DOI:10.1134/S1070363221040113

Reference yield:

Ethyl diphenylphosphinite (719-80-2) + N'-[2-Chloro-1-methyl-eth-(Z)-ylidene]-hydrazinecarboxylic acid methyl ester (103517-77-7) → N'-[2-(Diphenyl-phosphinoyl)-1-methyl-eth-(Z)-ylidene]-hydrazinecarboxylic acid methyl ester (103538-60-9) + N'-[2-(Diphenyl-phosphinoyl)-1-methyl-eth-(E)-ylidene]-hydrazinecarboxylic acid methyl ester (103518-03-2)

Guidance literature:

In toluene; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;

DOI:10.1055/s-1985-31424

Reference yield: 95.0%

N′-methoxycarbonylhydrazone of 1-(diphenylphosphoryl)propan-2-one (103518-03-2,103538-60-9) → 1-(diphenylphosphinoyl)propan-2-one (1733-52-4)

Guidance literature:

With hydrogenchloride; acetone; for 3h; Ambient temperature;

DOI:10.1055/s-1985-31424

upstream raw materials:

hydrazinecarboxylic acid methyl ester

1-(diphenylphosphinoyl)propan-2-one

Ethyl diphenylphosphinite

N'-[2-Chloro-1-methyl-eth-(Z)-ylidene]-hydrazinecarboxylic acid methyl ester

Downstream raw materials:

1-(diphenylphosphinoyl)propan-2-one

Refernces

• 1、 Corbel, Bernard,Medinger, Luc,Haelters, Jean Pierre,Sturtz, Georges. "An Efficient Synthesis of Dialkyl 2-Oxoalkanephosphonates and Diphenyl-2-oxoalkylphosphine Oxides from 1-Chloralkyl Ketones". . p. 1048 - 1051. Retrieved 2007/10/02.