Technology Process of 20-oxo-5α-pregnane-3α,12β-diyl 12-acetate 3-benzoate
There total 8 articles about 20-oxo-5α-pregnane-3α,12β-diyl 12-acetate 3-benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
toluene;
for 4h;
DOI:10.1021/jm3016365
- Guidance literature:
-
Multi-step reaction with 7 steps
1: pyridine / 24 h / 0 - 20 °C
2: potassium nitrite / N,N-dimethyl-formamide / 2 h / 130 °C
3: pyridine / benzene / 5.25 h / 0 °C
4: sodium tetrahydroborate / methanol; ethyl acetate / 2 h
5: acetic acid / 24 h / 180 °C / Sealed tube
6: acetic acid; chromium(VI) oxide / water; dichloromethane / 1.25 h / -8 °C
7: palladium 10% on activated carbon; hydrogen / toluene / 4 h
With
pyridine; chromium(VI) oxide; sodium tetrahydroborate; potassium nitrite; palladium 10% on activated carbon; hydrogen; acetic acid;
In
methanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; toluene; benzene;
DOI:10.1021/jm3016365
- Guidance literature:
-
Multi-step reaction with 5 steps
1: pyridine / benzene / 5.25 h / 0 °C
2: sodium tetrahydroborate / methanol; ethyl acetate / 2 h
3: acetic acid / 24 h / 180 °C / Sealed tube
4: acetic acid; chromium(VI) oxide / water; dichloromethane / 1.25 h / -8 °C
5: palladium 10% on activated carbon; hydrogen / toluene / 4 h
With
pyridine; chromium(VI) oxide; sodium tetrahydroborate; palladium 10% on activated carbon; hydrogen; acetic acid;
In
methanol; dichloromethane; water; ethyl acetate; toluene; benzene;
DOI:10.1021/jm3016365
