1-(3,3,3-trifluoropropyl)-3-cyclohexylurea

Base Information

• Chemical Name: 1-(3,3,3-trifluoropropyl)-3-cyclohexylurea
• CAS No.: 74788-86-6
• Molecular Formula: C₁₀H₁₇F₃N₂O
• Molecular Weight: 238.253
• Mol file: 74788-86-6.mol

Synonyms:

Chemical Property of 1-(3,3,3-trifluoropropyl)-3-cyclohexylurea

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1-(3,3,3-trifluoropropyl)-3-cyclohexylurea

There total 1 articles about 1-(3,3,3-trifluoropropyl)-3-cyclohexylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3,3-trifluoropropylamine (460-39-9) + Cyclohexyl isocyanate (3173-53-3) → 1-(3,3,3-trifluoropropyl)-3-cyclohexylurea (74788-86-6)

Guidance literature:

In diethyl ether; Ambient temperature;

DOI:10.1021/jm00185a015

Reference yield:

1-(3,3,3-trifluoropropyl)-3-cyclohexylurea (74788-86-6) → 1-(3,3,3-trifluoropropyl)-3-cyclohexyl-1-nitrosourea (74788-85-5)

Guidance literature:

With formic acid; sodium nitrite; at 5 ℃; for 0.75h;

DOI:10.1021/jm00185a015

upstream raw materials:

3,3,3-trifluoropropylamine

Cyclohexyl isocyanate

Downstream raw materials:

1-(3,3,3-trifluoropropyl)-3-cyclohexyl-1-nitrosourea

Refernces