11α,12α-Epoxy-13α-methyl-27-noroleana-14-ene-3β-ol acetate

Base Information

• Chemical Name: 11α,12α-Epoxy-13α-methyl-27-noroleana-14-ene-3β-ol acetate
• CAS No.: 2111-46-8
• Molecular Formula: C₃₂H₅₀O₃
• Molecular Weight: 482.747
• Mol file: 2111-46-8.mol

Synonyms:27-Norolean-14-en-3-ol,11,12-epoxy-13-methyl-, acetate, (3b,11a,12a,13a)- (9CI); D-Friedoolean-14-en-3-ol, 11,12-epoxy-, acetate, (3b,11a,12a)-; D-Friedoolean-14-en-3b-ol, 11a,12a-epoxy-, acetate (7CI,8CI); 11a,12a-Oxidotaraxeryl acetate; Marsformoxide B; [3S-(3a,4ab,6aa,8aa,12aa,12bb,12ca,13aa,13bb,13ca)]-1,2,3,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,12c,13a,13b,13c-Eicosahydro-4,4,6a,8a,11,11,12b,13c-octamethylpiceno[13,14-b]oxiren-3-olacetate

Chemical Property of 11α,12α-Epoxy-13α-methyl-27-noroleana-14-ene-3β-ol acetate

Chemical Property:

• Melting Point: 306-307℃ (chloroform )
• Boiling Point: 520.7±50.0 °C(Predicted)
• PSA: 38.83000
• Density: 1.08±0.1 g/cm3(Predicted)
• LogP: 7.72690

Purity/Quality:

99% ^*data from raw suppliers

MarsformoxideB 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 11α,12α-Epoxy-13α-methyl-27-noroleana-14-ene-3β-ol acetate

There total 4 articles about 11α,12α-Epoxy-13α-methyl-27-noroleana-14-ene-3β-ol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

β-amyrin acetate (1616-93-9,33055-28-6,64200-19-7) → 11α,12α-oxidotaraxerol (3866-77-1) + 11α,12α-epoxytaraxer-14-en-3β-yl acetate (2111-46-8)

Guidance literature:

With selenium(IV) oxide; dihydrogen peroxide; In tert-butyl alcohol; for 60h; Heating;

DOI:10.1016/S0040-4020(01)90326-6

Reference yield:

11α,12α-oxidotaraxerol (3866-77-1) + acetic anhydride (108-24-7) → 11α,12α-epoxytaraxer-14-en-3β-yl acetate (2111-46-8)

Guidance literature:

With pyridine;

DOI:10.1016/S0040-4020(01)90326-6

Reference yield:

→ 11α,12α-epoxytaraxer-14-en-3β-yl acetate (2111-46-8)

Guidance literature:

11α.12α-Oxido-taraxer-14-en-3β-ol, Acetanhydrid, Py. in CH2Cl2;

DOI:10.1021/jo01017a002

upstream raw materials:

β-amyrin acetate

11α,12α-oxidotaraxerol

acetic anhydride

Refernces