Technology Process of (6Z,8E,10E,14Z)-(5S,12R)-5,12-Bis-(tert-butyl-diphenyl-silanyloxy)-icosa-6,8,10,14-tetraenedioic acid dimethyl ester
There total 7 articles about (6Z,8E,10E,14Z)-(5S,12R)-5,12-Bis-(tert-butyl-diphenyl-silanyloxy)-icosa-6,8,10,14-tetraenedioic acid dimethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: imidazole / dimethylformamide / 0 - 25 °C
2: pyridinium p-toluene sulphonate / methanol / 48 °C
3: CrO3.2pyr., celite / CH2Cl2 / 0 °C
4: LDA / tetrahydrofuran / -78 - 25 °C
5: hydrogen / Lindlar
With
1H-imidazole; Celite; hydrogen; pyridinium p-toluenesulfonate; dipyridine chromium trioxide; lithium diisopropyl amide;
Lindlar's catalyst;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)84400-7
- Guidance literature:
-
Multi-step reaction with 2 steps
1: LDA / tetrahydrofuran / -78 - 25 °C
2: hydrogen / Lindlar
With
hydrogen; lithium diisopropyl amide;
Lindlar's catalyst;
In
tetrahydrofuran;
DOI:10.1016/S0040-4039(00)84400-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1: CrO3.2pyr., celite / CH2Cl2 / 0 °C
2: LDA / tetrahydrofuran / -78 - 25 °C
3: hydrogen / Lindlar
With
Celite; hydrogen; dipyridine chromium trioxide; lithium diisopropyl amide;
Lindlar's catalyst;
In
tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)84400-7
