menaquinol

Base Information

• Chemical Name: menaquinol
• CAS No.: 39776-47-1
• Molecular Formula: C₄₆H₆₆O₂
• Molecular Weight: 651.029
• Mol file: 39776-47-1.mol

Synonyms:

Chemical Property of menaquinol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of menaquinol

There total 6 articles about menaquinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

menaquinone-7 (2124-57-4,27670-94-6) → menaquinol (39776-47-1)

Guidance literature:

With acetic acid; zinc; In methanol; at 20 ℃; Reagent/catalyst;

Reference yield:

betulaprenol 6 (77551-14-5) → menaquinol (39776-47-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: phosphorus trichloride / N,N-dimethyl-formamide / 20 °C

2.1: n-butyllithium / tetrahydrofuran / -7 - 0 °C

3.1: zirconocene dichloride / toluene / 1 h / 0 °C

3.2: 1 h / -20 °C

4.1: zinc; acetic acid / methanol / 20 °C

With n-butyllithium; zirconocene dichloride; acetic acid; zinc; phosphorus trichloride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; toluene;

Reference yield:

C30H49Cl → menaquinol (39776-47-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran / -7 - 0 °C

2.1: zirconocene dichloride / toluene / 1 h / 0 °C

2.2: 1 h / -20 °C

3.1: zinc; acetic acid / methanol / 20 °C

With n-butyllithium; zirconocene dichloride; acetic acid; zinc; In tetrahydrofuran; methanol; toluene;

upstream raw materials:

betulaprenol 6

menaquinone-7

Refernces

• 1、 -. "Menaquinol Compositions and Methods of Treatment". . . Retrieved 2020/04/09.