(6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)phenylcarbinol

Base Information

• Chemical Name: (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)phenylcarbinol
• CAS No.: 58024-46-7
• Molecular Formula: C₂₆H₂₅NO₅
• Molecular Weight: 431.488
• Mol file: 58024-46-7.mol

Synonyms:

Chemical Property of (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)phenylcarbinol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)phenylcarbinol

There total 4 articles about (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)phenylcarbinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Papaverine (58-74-2) → (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)phenylcarbinol (58024-46-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / O₂ / dimethylsulfoxide / 6 h / 40 °C

2: 1.) magnesium / 1.) ether, 2.)a) ether, 0 deg C, 1 h, b) 20 deg C, 1 h

With oxygen; magnesium; In dimethyl sulfoxide;

DOI:10.1007/BF00534392

Reference yield:

papaveraldine (522-57-6) → (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)phenylcarbinol (58024-46-7) + 1,2-bis(3,4-dimethoxyphenyl)-1,2-bis(6,7-dimethoxyisoquinolin-1-yl)ethanol

Guidance literature:

With bromobenzene; magnesium; Yield given. Multistep reaction. Yields of byproduct given; 1.) ether, 2.)a) ether, 0 deg C, 1 h, b) 20 deg C, 1 h;

DOI:10.1007/BF00534392

Reference yield:

bromobenzene (108-86-1,52753-63-6) + papaveraldine (522-57-6) → (6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)phenylcarbinol (58024-46-7) + 1,2-bis(3,4-dimethoxyphenyl)-1,2-bis(6,7-dimethoxyisoquinolin-1-yl)ethanol

Guidance literature:

With magnesium; Yield given. Multistep reaction. Yields of byproduct given; 1.) ether, 2.)a) ether, 0 deg C, 1 h, b) 20 deg C, 1 h;

DOI:10.1007/BF00534392

upstream raw materials:

bromobenzene

papaveraldine

Papaverine

Refernces