1-(azidomethyl)-2-methylbenzene(SALTDATA: FREE)

Base Information

• Chemical Name: 1-(azidomethyl)-2-methylbenzene(SALTDATA: FREE)
• CAS No.: 126799-83-5
• Molecular Formula: C8H9N3
• Molecular Weight: 147.18
• Hs Code.: 2929909090
• Mol file: 126799-83-5.mol

Synonyms:Bis(o-methylbenzoyl) peroxide;di-o-toluoyl peroxide;Peroxide,bis(2-methylbenzoyl);2-methylbenzyl azide;2-methylbenzoyl peroxide;bis(2-methylbenzoyl) peroxide;2-methylbenzoic peroxyanhydride;o-methylbenzyl azide;Bis(o-toluoyl) peroxide;

Chemical Property of 1-(azidomethyl)-2-methylbenzene(SALTDATA: FREE)

Chemical Property:

• Flash Point: -30℃
• PSA: 49.75000
• LogP: 2.25806
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(Azidomethyl)-2-methylbenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 4860454
• Hazard Codes: F,Xi
• Statements: 11-38
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(azidomethyl)-2-methylbenzene(SALTDATA: FREE)

There total 11 articles about 1-(azidomethyl)-2-methylbenzene(SALTDATA: FREE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ 2-methylbenzylazide (126799-83-5)

Guidance literature:

Reference yield: 91.0%

2-methylbenzyl bromide (89-92-9) → 2-methylbenzylazide (126799-83-5)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 20 - 80 ℃; for 4h;

DOI:10.1002/cmdc.201402374

Reference yield: 77.0%

o-xylene (95-47-6) → 2-methylbenzylazide (126799-83-5)

Guidance literature:

With Cu(2,9-bis(panisyl)-1,10-phenanthroline)₂Cl; 1-azido-1λ³-benzo[d][1,2]iodaoxol-3(1H)-one; In acetonitrile; at 20 ℃; for 16h; Sealed tube; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.6b00512

upstream raw materials:

2-methylbenzyl bromide

1-chloromethyl-2-methylbenzene

o-xylene

2-methyl-benzyl alcohol

Downstream raw materials:

1-(2-methylbenzyl)-1H-1,2,3-triazole

ortho-methylbenzylamine

N-((1-(2-methylbenzyl)-1H-1,2,3-triazol-4-yl)methyl)-5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-amine

o-xylyl P-triphenyliminophosphorane

Refernces

• 1、 Varma, Rajender S.,Naicker, Kannan P.,Aschbeiger, Jason. "A facile preparation of alkyl azides from alkyl bromides and sodium azide using 18-crown-6 ether doped clay". . p. 2823 - 2830. Retrieved 1999.
• 2、 Chen, Wei-Chen,Gandeepan, Parthasarathy,Tsai, Chia-Hung,Luo, Ching-Zong,Rajamalli, Pachaiyappan,Cheng, Chien-Hong. "A concise synthesis of quinolinium, and biquinolinium salts and biquinolines from benzylic azides and alkenes promoted by copper(II) species". . p. 63390 - 63397. Retrieved 2016.
• 3、 -. "NOVEL DIBENZOOXAPHOSPHININE OXIDE DERIVATIVE COMPOUNDS AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DEGENERATIVE DISEASE COMPRISING THE SAME AS AN ACTIVE INGREDIENT". Paragraph 0137-0140. . Retrieved 2021/03/23.
• 4、 Rezaei, Elham Babazadeh,Abedinifar, Fahimeh,Azizian, Homa,Montazer, Mohammad Nazari,Asadi, Mehdi,Hosseini, Samanesadat,Sepehri, Saghi,Mohammadi-Khanaposhtani, Maryam,Biglar, Mahmood,Larijani, Bagher,Amanlou, Massoud,Mahdavi, Mohammad. "Design, synthesis, and evaluation of metronidazole-1,2,3-triazole derivatives as potent urease inhibitors". . p. 4217 - 4226. Retrieved 2021/04/26.