C₅₁H₅₄O₆

Base Information

• Chemical Name: C₅₁H₅₄O₆
• CAS No.: 1449214-06-5
• Molecular Formula: C₅₁H₅₄O₆
• Molecular Weight: 762.986
• Mol file: 1449214-06-5.mol

Synonyms:

Chemical Property of C₅₁H₅₄O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₁H₅₄O₆

There total 8 articles about C₅₁H₅₄O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phorbol (17673-25-5) → C51H54O6 (1449214-06-5)

Guidance literature:

Multi-step reaction with 8 steps

1: sulfuric acid / water / 90 °C

2: pyridine / 50 °C

3: hydrazine hydrate; acetic acid / methanol

4: N-ethyl-N,N-diisopropylamine / toluene / 140 °C

5: toluene; dichloromethane / -78 - 20 °C

6: ethyl acetate / UV-irradiation

7: barium hydroxide nonahydrate / methanol

8: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap

With pyridine; dmap; sulfuric acid; barium hydroxide nonahydrate; hydrazine hydrate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; water; ethyl acetate; toluene;

DOI:10.1073/pnas.1302634110

Reference yield:

(3aR,6aS,7R,10R,10aR,10bS)-3a,10a-dihydroxy-5-(hydroxymethyl)-2,10-dimethyl-7-(prop-1-en-2-yl)-3a,4,6a,7,10,10a-hexahydrobenzo[e]azulene-3,8(9H,10bH)-dione (18325-99-0) → C51H54O6 (1449214-06-5)

Guidance literature:

Multi-step reaction with 7 steps

1: pyridine / 50 °C

2: hydrazine hydrate; acetic acid / methanol

3: N-ethyl-N,N-diisopropylamine / toluene / 140 °C

4: toluene; dichloromethane / -78 - 20 °C

5: ethyl acetate / UV-irradiation

6: barium hydroxide nonahydrate / methanol

7: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap

With pyridine; dmap; barium hydroxide nonahydrate; hydrazine hydrate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; ethyl acetate; toluene;

DOI:10.1073/pnas.1302634110

Reference yield:

C39H42N2O4 (1173884-72-4) → C51H54O6 (1449214-06-5)

Guidance literature:

Multi-step reaction with 4 steps

1: toluene; dichloromethane / -78 - 20 °C

2: ethyl acetate / UV-irradiation

3: barium hydroxide nonahydrate / methanol

4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap

With dmap; barium hydroxide nonahydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; dichloromethane; ethyl acetate; toluene;

DOI:10.1073/pnas.1302634110

upstream raw materials:

phorbol

(3aR,6aS,7R,10R,10aR,10bS)-3a,10a-dihydroxy-5-(hydroxymethyl)-2,10-dimethyl-7-(prop-1-en-2-yl)-3a,4,6a,7,10,10a-hexahydrobenzo[e]azulene-3,8(9H,10bH)-dione

(1,2,3,4-tetrahydro-5-naphthyl)acetic acid

C₂₀-O-trityl-prostratin-ol

Refernces