Takinib

Base Information

• Chemical Name: Takinib
• CAS No.: 1111556-37-6
• Molecular Formula: C₁₈H₁₈N₄O₂
• Molecular Weight: 322.367
• Mol file: 1111556-37-6.mol

Synonyms:

Chemical Property of Takinib

Chemical Property:

• PKA: 12.13±0.43(Predicted)
• Density: 1.30±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Takinib ≥98%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Takinib

There total 1 articles about Takinib which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-carboxybenzamide (4481-28-1) + 1-propyl-1H-benzo[d]imidazol-2-amine (57667-50-2) → N-(1-propyl-1H-benzo[d]imidazol-2-yl)isophthalamide (1111556-37-6)

Guidance literature:

3-carboxybenzamide; 1-propyl-1H-benzo[d]imidazol-2-amine; With 4-methyl-morpholine; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h;

With dmap; In N,N-dimethyl-formamide; for 12h; Solvent; Temperature;

upstream raw materials:

3-carboxybenzamide

1-propyl-1H-benzo[d]imidazol-2-amine

Refernces