Technology Process of C19H22BrN
There total 5 articles about C19H22BrN which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate;
In
methanol; isopropyl alcohol;
at 0 ℃;
for 1h;
optical yield given as %de;
DOI:10.1021/jo300277y
- Guidance literature:
-
Multi-step reaction with 3 steps
1: aluminum (III) chloride / dichloromethane / 0.5 h / 0 °C
2: toluene-4-sulfonic acid / toluene / 1 h / 50 °C
3: sodium tetrahydroborate / methanol; isopropyl alcohol / 1 h / 0 °C
With
aluminum (III) chloride; sodium tetrahydroborate; toluene-4-sulfonic acid;
In
methanol; dichloromethane; isopropyl alcohol; toluene;
1: Friedel Crafts alkylation / 1: Friedel Crafts alkylation;
DOI:10.1021/jo300277y
- Guidance literature:
-
Multi-step reaction with 5 steps
1: bromine; potassium carbonate / water
2: thionyl chloride / dichloromethane / 30 °C / Reflux
3: aluminum (III) chloride / dichloromethane / 0.5 h / 0 °C
4: toluene-4-sulfonic acid / toluene / 1 h / 50 °C
5: sodium tetrahydroborate / methanol; isopropyl alcohol / 1 h / 0 °C
With
aluminum (III) chloride; sodium tetrahydroborate; thionyl chloride; bromine; potassium carbonate; toluene-4-sulfonic acid;
In
methanol; dichloromethane; water; isopropyl alcohol; toluene;
3: Friedel Crafts alkylation / 3: Friedel Crafts alkylation;
DOI:10.1021/jo300277y