[2-(Ethoxymethyl)phenyl]methanamine

Base Information

• Chemical Name: [2-(Ethoxymethyl)phenyl]methanamine
• CAS No.: 28837-92-5
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.235
• European Community (EC) Number: 822-085-0
• Mol file: 28837-92-5.mol

Synonyms:[2-(ethoxymethyl)phenyl]methanamine;28837-92-5;1-[2-(ethoxymethyl)phenyl]methanamine;(2-(ethoxymethyl)phenyl)methanamine;SCHEMBL9862096;XRHPSGUGMIFVLP-UHFFFAOYSA-N;AKOS000146369;MCULE-5647422736;DB-102168;CS-0246586;EN300-33343;G25743

Chemical Property of [2-(Ethoxymethyl)phenyl]methanamine

Chemical Property:

• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 165.115364102
• Heavy Atom Count: 12
• Complexity: 116

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOCC1=CC=CC=C1CN

Technology Process of [2-(Ethoxymethyl)phenyl]methanamine

There total 6 articles about [2-(Ethoxymethyl)phenyl]methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(ethoxymethyl)benzonitrile (1016708-78-3) → 2-ethoxymethyl-benzylamine (28837-92-5)

Guidance literature:

With acetic acid; platinum; Hydrogenation;

DOI:10.1021/ja01306a048

Reference yield:

2-ethoxymethyl-thiobenzoic acid amide (1016884-62-0) → 2-ethoxymethyl-benzylamine (28837-92-5)

Guidance literature:

With hydrogenchloride; zinc;

DOI:10.1021/ja01306a048

Reference yield:

2-(ethoxymethyl)benzonitrile (1016708-78-3) → 2-ethoxymethyl-benzylamine (28837-92-5) + bis-(2-ethoxymethyl-benzyl)-amine (861338-62-7)

Guidance literature:

With nickel; decalin; at 130 ℃; Hydrogenation;

upstream raw materials:

2-(ethoxymethyl)benzonitrile

2-ethoxymethyl-thiobenzoic acid amide

decalin

2-(bromomethyl)benzonitrile

Downstream raw materials:

o-chloromethylbenzylamine

2-ethoxymethyl-benzyl alcohol

(2-ethoxymethyl-phenyl)-acetonitrile

ethyl-(2-bromomethyl-benzyl)-ether