1-bromo-3-phenylcyclopropene

Base Information

• Chemical Name: 1-bromo-3-phenylcyclopropene
• CAS No.: 865351-09-3
• Molecular Formula: C₉H₇Br
• Molecular Weight: 195.059
• Mol file: 865351-09-3.mol

Synonyms:

Chemical Property of 1-bromo-3-phenylcyclopropene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-bromo-3-phenylcyclopropene

There total 3 articles about 1-bromo-3-phenylcyclopropene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

cis/trans-1,1,2-tribromo-3-phenylcyclopropane → 1-bromo-3-phenylcyclopropene (865351-09-3)

Guidance literature:

With methyllithium;

DOI:10.1070/MC2004v014n06ABEH002061

Reference yield:

cis/trans-1,1,2-tribromo-3-phenylcyclopropane → (3-bromopropa-1,2-dien-1-yl)benzene (33992-52-8) + phenylpropargyl bromide (50874-14-1) + 1-bromo-3-phenylcyclopropene (865351-09-3)

Guidance literature:

With methyllithium; In diethyl ether; at -82 - -40 ℃; for 0.533333h; Inert atmosphere;

DOI:10.1016/j.tet.2009.09.098

Reference yield:

2,2-dibromo-3-phenylcyclopropanecarboxylic acid → 1-bromo-3-phenylcyclopropene (865351-09-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / methyllithium

With methyllithium; 1: Hunsdiecker reaction;

DOI:10.1070/MC2004v014n06ABEH002061

Downstream raw materials:

(3-bromopropa-1,2-dien-1-yl)benzene

phenylpropargyl bromide

Refernces

• 1、 Sheshenev, Andrey E.,Baird, Mark S.,Croft, Anna K.,Bolesov, Ivan G.. "Generation and stereoselective transformations of 3-phenylcyclopropene". experimental part. p. 10036 - 10046. Retrieved 2010/02/27.