6''-O-<2-(methoxycarbonyl)acetyl>isoquercitrin

Base Information

• Chemical Name: 6''-O-<2-(methoxycarbonyl)acetyl>isoquercitrin
• CAS No.: 153874-66-9
• Molecular Formula: C₂₅H₂₄O₁₅
• Molecular Weight: 564.457
• Mol file: 153874-66-9.mol

Synonyms:

Chemical Property of 6''-O-<2-(methoxycarbonyl)acetyl>isoquercitrin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6''-O-<2-(methoxycarbonyl)acetyl>isoquercitrin

There total 1 articles about 6''-O-<2-(methoxycarbonyl)acetyl>isoquercitrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

isoquercetin (482-35-9) + 2-chloroethyl methyl propanedioate (131072-45-2) → 3''-O-<2-(methoxycarbonyl)acetyl>isoquercitrin + 6''-O-<2-(methoxycarbonyl)acetyl>isoquercitrin (153874-66-9) + 3'',6''-di-O-<2-(methoxycarbonyl)acetyl>isoquercitrin

Guidance literature:

In pyridine; at 45 ℃; for 168h; subtilisin;

DOI:10.1002/hlca.19930760823

Reference yield: 33.0%

6''-O-<2-(methoxycarbonyl)acetyl>isoquercitrin (153874-66-9) → isoquercetin (482-35-9) + quercetin 3-O-(6′′-O-malonyl)-β-glucopyranoside (96862-01-0)

Guidance literature:

With phosphate buffer pH 7; pig-liver esterase; In N,N-dimethyl-formamide; for 24h; Product distribution; Ambient temperature; various enzymes;

DOI:10.1002/hlca.19930760823

Reference yield:

6''-O-<2-(methoxycarbonyl)acetyl>isoquercitrin (153874-66-9) → ((2R,3S,4S,5R,6S)-6-((2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl cinnamate

Guidance literature:

Multi-step reaction with 2 steps

1: 59 percent / pig-liver esterase, phosphate buffer pH 7 / dimethylformamide / 24 h / Ambient temperature; various enzymes

2: 32 mg / piperidine, molecular sieves / pyridine / 2.5 h / 60 °C

With piperidine; molecular sieve; phosphate buffer pH 7; pig-liver esterase; In pyridine; N,N-dimethyl-formamide;

DOI:10.1002/hlca.19930760823

upstream raw materials:

isoquercetin

2-chloroethyl methyl propanedioate

Downstream raw materials:

isoquercetin

quercetin 3-O-(6′′-O-malonyl)-β-glucopyranoside

Refernces