N-Propyl-2,4-dinitroaniline

Base Information

• Chemical Name: N-Propyl-2,4-dinitroaniline
• CAS No.: 13059-84-2
• Molecular Formula: C9H11N3O4
• Molecular Weight: 225.204
• Hs Code.: 2921420090
• Mol file: 13059-84-2.mol

Synonyms:.2,4-dinitro-N-propyl-aniline;.N-propyl-2,4-dinitrobenzenamine;N-(2,4-dinitrophenyl)propylamine;2,4-DINITRO-N-PROPYLANILINE;.N-propyl-2,4-dinitroaniline;.2,4-dinitro-N-propylaniline;.2,4-dinitro-N-n-propylaniline;

Chemical Property of N-Propyl-2,4-dinitroaniline

Chemical Property:

• PSA: 103.67000
• LogP: 3.44430

Purity/Quality:

98%Min ^*data from raw suppliers

2,4-DINITRO-N-PROPYLANILINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Propyl-2,4-dinitroaniline

There total 34 articles about N-Propyl-2,4-dinitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

propylamine (107-10-8,42939-71-9) + 1-chloro-2,4-dinitro-benzene (97-00-7) → 2,4-dinitro-N-propylaniline (13059-84-2)

Guidance literature:

In dichloromethane; at 20 ℃; for 1h;

DOI:10.1002/hlca.201000253

Reference yield: 93.0%

propylamine (107-10-8,42939-71-9) + 2,4-dinitrobenzenesulfonic acid (89-02-1) → 2,4-dinitro-N-propylaniline (13059-84-2)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 0.5h; Green chemistry;

DOI:10.1021/acs.orglett.8b03730

Reference yield: 86.0%

propylamine (107-10-8,42939-71-9) + 5-amino-1-(2,4-dinitrophenyl)-1H-pyrazole-4-carbonitrile (75008-95-6) → 2,4-dinitro-N-propylaniline (13059-84-2)

Guidance literature:

In ethanol; for 2h; Reflux;

DOI:10.3184/030823408X338693

upstream raw materials:

propylamine

2,4-dinitrobromobenzene

(2,4-dinitrophenyl)dipropylamine

2,4-dinitro-N-nitroso-N-propyl-aniline

Downstream raw materials:

2,4,6,N-tetranitro-N-propyl-aniline

N¹-n-propyl-4-nitro-benzene-1,2-diamine

Refernces

• 1、 Jain, Ajay K.,Velu, V. K.,Sarma, K. N.. "KINETIC STUDIES AND MICELLAR EFFECT ON THE AMINOLYSIS OF CERTAIN O-ARYL OXIMES". . p. 2569 - 2574. Retrieved 1988.
• 2、 Gazitúa, Marcela,Tapia, Ricardo A.,Contreras, Renato,Campodónico, Paola R.. "Effect of the nature of the nucleophile and solvent on an SNAr reaction". . p. 260 - 264. Retrieved 2018.
• 3、 Wei, Tingwen,Lu, Sheng,Sun, Jiahui,Xu, Zhijun,Yang, Xiao,Wang, Fang,Ma, Yang,Shi, Yun Stone,Chen, Xiaoqiang. "RETRACTED ARTICLE: Sanger's Reagent Sensitized Photocleavage of Amide Bond for Constructing Photocages and Regulation of Biological Functions". supporting information. p. 3806 - 3813. Retrieved 2020/03/10.
• 4、 Valvi, Arun,Tiwari, Shraeddha. "“Zero VOC” Synthetic Strategy – Aromatic Amination Reactions in Deep Eutectic Solvents". . p. 4933 - 4939. Retrieved 2018/09/11.