5-(D-arabino-tetroxybutyl)-2-phenyl-3-furoic acid

Base Information

• Chemical Name: 5-(D-arabino-tetroxybutyl)-2-phenyl-3-furoic acid
• CAS No.: 61761-75-9
• Molecular Formula: C₁₅H₁₆O₇
• Molecular Weight: 308.288
• Mol file: 61761-75-9.mol

Synonyms:

Chemical Property of 5-(D-arabino-tetroxybutyl)-2-phenyl-3-furoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(D-arabino-tetroxybutyl)-2-phenyl-3-furoic acid

There total 5 articles about 5-(D-arabino-tetroxybutyl)-2-phenyl-3-furoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

ethyl 2-phenyl-5-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-furoate (81661-27-0) → 5-(D-arabino-tetroxybutyl)-2-phenyl-3-furoic acid (61761-75-9)

Guidance literature:

alkaline hydrolyis;

Reference yield: 64.0%

5-(D-arabino-tetroxybutyl)-2-nitrile-2-phenyl-furan (81661-24-7) → 5-(D-arabino-tetroxybutyl)-2-phenyl-3-furoic acid (61761-75-9)

Guidance literature:

alkaline hydrolyis;

Reference yield:

ethyl 3-oxo-3-phenylpropionate (94-02-0) → 5-(D-arabino-tetroxybutyl)-2-phenyl-3-furoic acid (61761-75-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 57 percent / ZnCl₂ / ethanol / 70 °C

2: 82 percent / alkaline hydrolyis

With zinc(II) chloride; In ethanol;

upstream raw materials:

ethyl 2-phenyl-5-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-furoate

5-(D-arabino-tetroxybutyl)-2-nitrile-2-phenyl-furan

Benzoylacetonitrile

ethyl 3-oxo-3-phenylpropionate

Downstream raw materials:

2-phenyl-furan-3,5-dicarboxylic acid

5-formyl-2-phenyl-furan-3-carboxylic acid

Refernces