3-Hydrazinoquinoxaline-2-thiol

Base Information

• Chemical Name: 3-Hydrazinoquinoxaline-2-thiol
• CAS No.: 13080-21-2
• Molecular Formula: C8H8N4S
• Molecular Weight: 192.244
• Hs Code.: 2933990090
• European Community (EC) Number: 804-910-6
• DSSTox Substance ID: DTXSID70354764
• Wikidata: Q82133158
• ChEMBL ID: CHEMBL4874776
• Mol file: 13080-21-2.mol

Synonyms:13080-21-2;3-hydrazinoquinoxaline-2-thiol;HPi1;3-hydrazinylquinoxaline-2-thiol;3-Hydrazino-quinoxaline-2-thiol;3-hydrazinyl-1H-quinoxaline-2-thione;3-Hydrazinylquinoxaline-2(1H)-thione;CHEMBL4874776;Oprea1_388342;CBDivE_004366;3-Hydrazino-2-quinoxalinethiol;SCHEMBL2269856;DTXSID70354764;HMS1578P09;CCG-2360;BBL010512;BDBM50572785;MFCD00457014;STK031331;AKOS000274400;AKOS030241061;VS-02536;HY-120536;CS-0078290;3-hydrazinyl-1,2-dihydroquinoxaline-2-thione;E84314;EN300-243598

Chemical Property of 3-Hydrazinoquinoxaline-2-thiol

Chemical Property:

• Vapor Pressure: 7.41E-06mmHg at 25°C
• Boiling Point: 376.1oC at 760 mmHg
• Flash Point: 181.3oC
• PSA: 102.63000
• Density: 1.55g/cm3
• LogP: 1.97740
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 192.04696745
• Heavy Atom Count: 13
• Complexity: 251

Purity/Quality:

99% ^*data from raw suppliers

3-Hydrazinylquinoxaline-2-thiol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)NC(=S)C(=N2)NN

Technology Process of 3-Hydrazinoquinoxaline-2-thiol

There total 2 articles about 3-Hydrazinoquinoxaline-2-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1,4-dihydro-quinoxaline-2,3-dithione (1199-03-7) → 2-mercapto-3-hydrazinoquinoxaline (13080-21-2)

Guidance literature:

With hydrazine hydrate; In methanol; Reflux;

DOI:10.1080/00958972.2010.487938

Reference yield:

→ 3-Hydrazino-2-mercapto-chinoxalin (13080-21-2)

Guidance literature:

2,3-Dimercapto-chinoxalin, W., Hydrazinhydrat, 100grad;

Reference yield:

2-mercapto-3-hydrazinoquinoxaline (13080-21-2) → quinoxaline-2,3-dione (15804-19-0,6287-20-3)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

1,4-dihydro-quinoxaline-2,3-dithione

Downstream raw materials:

quinoxaline-2,3-dione

Refernces

• 1、 Kurdekar, Gurunath S.,Kulkarni, Naveen V.,Budagumpi, Srinivasa,Sathisha,Bevinhalli, Nagaraj H.,Revankar, Vidyanand K.. "Construction of mononuclear transition metal(II) complexes with bi- and tridentate, neutral hydrazone ligands with a quinoxaline hub". . p. 2172 - 2180. Retrieved 2010.