2,6-dimethylphenyl isonitrile

Base Information

• Chemical Name: 2,6-dimethylphenyl isonitrile
• CAS No.: 119072-54-7
• Molecular Formula: C₉H₉N
• Molecular Weight: 131.177
• Mol file: 119072-54-7.mol

Synonyms:

Chemical Property of 2,6-dimethylphenyl isonitrile

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-dimethylphenyl isonitrile

There total 26 articles about 2,6-dimethylphenyl isonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cobalt(Cl)2(2,6-xylyl isocyanide)4 (67662-53-7) + Benzyl isocyanide (88333-03-3,10340-91-7) → CoCl2(CNC6H3(CH3)2)3(CNCH2C6H5) + 2,6-dimethylphenyl isonitrile (119072-54-7,2769-71-3)

Guidance literature:

In benzene; at 80 °C, under Ar;

Reference yield: 85.0%

{Ir2(CN-2,6-Me2C6H3)5(bis(dimethylphosphino)methane)2}{PF6}2 → Ir2(2,6-Me2C6H3CN)4(dmpm)2 + 2,6-dimethylphenyl isonitrile (119072-54-7,2769-71-3)

Guidance literature:

With sodium amalgam; In benzene; under N2, excess sodium amalgam, stirred for 3 days; decanted, filtered, evapn. under vac., washed with benzene (removal of isocyanide), recrystn. (benzene/hexane); elem. anal.;

DOI:10.1021/ja00202a023

Reference yield: 65.0%

N-acetyl-N'-(2,6-dimethylphenylaminomethylene)hydrazine (112547-81-6) → 2,6-dimethylphenyl isonitrile (119072-54-7,2769-71-3) + C22H26N6O2 (107322-05-4,112574-83-1)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; for 48h; Ambient temperature;

upstream raw materials:

2,6-dimethylformanilide

N-acetyl-N'-(2,6-dimethylphenylaminomethylene)hydrazine

N-(2,6-dimethylphenylaminomethylene)-N'-methoxycarbonylhydrazine

N-benzoyl-N'-(2,6-dimethylphenylaminomethylene)hydrazine

Downstream raw materials:

3-[N-(2,6-dimethyl-phenyl)-formimidoyl]-3H-benzooxazole-2-thione

3-(2,6-dimethylphenyl)-1,1-diethylurea

N'-(2,6-dimethylphenyl)-N-methyl-N-phenyl-urea

1-(2,6-xylylimino)propane

Refernces

• 1、 Brennessel, William W.,Kucera, Benjamin E.,Young, Victor G.,Ellis, John E.. "Crystal structures and spectroscopic characterization of MBr2(CNXyl)n (M = Fe and Co, n = 4; M = Ni, n = 2; Xyl = 2,6-dimethylphenyl), and of formally zero-valent iron as a cocrystal of Fe(CNXyl)5 and Fe2(CNXyl)9". . p. 1118 - 1127. Retrieved 2019.
• 2、 Deaton, Joseph C.,Taliaferro, Chelsea M.,Pitman, Catherine L.,Czerwieniec, Rafa?,Jakubikova, Elena,Miller, Alexander J. M.,Castellano, Felix N.. "Excited-State Switching between Ligand-Centered and Charge Transfer Modulated by Metal-Carbon Bonds in Cyclopentadienyl Iridium Complexes". . p. 15445 - 15461. Retrieved 2018.
• 3、 Gomez, Manuel,Ilarduya, Jesus M. Martinez de,Royo, Pascual. "Reactions of metallocene niobium(III) isocyanide complexes with oxidizing reagents". . p. 197 - 204. Retrieved 1989.
• 4、 Weidlich, Frauke,Esumi, Naoto,Chen, Dongyang,Mück-Lichtenfeld, Christian,Zysman-Colman, Eli,Studer, Armido. "Mild C?F Activation in Perfluorinated Arenes through Photosensitized Insertion of Isonitriles at 350 nm". . p. 376 - 383. Retrieved 2019/11/19.