2'-O-Methylhelichrysetin

Base Information

• Chemical Name: 2'-O-Methylhelichrysetin
• CAS No.: 123316-64-3
• Molecular Formula: C₁₇H₁₆O₅
• Molecular Weight: 300.311
• Mol file: 123316-64-3.mol

Synonyms:

Chemical Property of 2'-O-Methylhelichrysetin

Chemical Property:

• Melting Point: 192-193 °C
• Boiling Point: 556.0±50.0 °C(Predicted)
• PKA: 7.18±0.25(Predicted)
• Density: 1.279±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

2'-O-Methylhelichrysetin ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2'-O-Methylhelichrysetin

There total 5 articles about 2'-O-Methylhelichrysetin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,6-dihydroxy-2-methoxyacetophenone (3602-54-8) → (E)-4,4'-dihydroxy-2',6'-dimethoxychalcone (123316-64-3)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / acetone / 10 h / Heating

2: 200 mg / K₂CO₃ / acetone / 8 h / Heating

3: 200 mg / 4percent methanolic HCl / 0.08 h / Heating

With hydrogenchloride; potassium carbonate; In acetone;

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → (E)-4,4'-dihydroxy-2',6'-dimethoxychalcone (123316-64-3)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / acetone / 0.75 h

2: 250 mg / 4percent methanolic KOH / 72 h / Ambient temperature

3: 200 mg / 4percent methanolic HCl / 0.08 h / Heating

With hydrogenchloride; potassium hydroxide; potassium carbonate; In acetone;

Reference yield:

4-ethoxymethoxy-2-hydroxy-6-methoxy-acetophenone (158017-91-5) → (E)-4,4'-dihydroxy-2',6'-dimethoxychalcone (123316-64-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 200 mg / K₂CO₃ / acetone / 8 h / Heating

2: 200 mg / 4percent methanolic HCl / 0.08 h / Heating

With hydrogenchloride; potassium carbonate; In acetone;

upstream raw materials:

4-ethoxymethoxy-2,6-dimethoxyacetophenone

4,4'-diethoxymethoxy-2',6'-dimethoxychalcone

4,6-dihydroxy-2-methoxyacetophenone

4-(ethyloxymethoxy)benzaldehyde

Refernces