6-O-benzoyl-3-O-chloroacetyl-galactal

Base Information

• Chemical Name: 6-O-benzoyl-3-O-chloroacetyl-galactal
• CAS No.: 118357-00-9
• Molecular Formula: C₁₅H₁₅ClO₆
• Molecular Weight: 326.733
• Mol file: 118357-00-9.mol

Synonyms:

Chemical Property of 6-O-benzoyl-3-O-chloroacetyl-galactal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-O-benzoyl-3-O-chloroacetyl-galactal

There total 4 articles about 6-O-benzoyl-3-O-chloroacetyl-galactal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

Lipase P + vinyl chloroacetate (2549-51-1) + 6-O-Benzoyl-D-glucal (58871-05-9) → 6-O-benzoyl-3-O-chloroacetyl-glucal (118357-00-9,118396-89-7,126453-38-1)

Guidance literature:

In 1,2-dimethoxyethane;

Reference yield: 80.0%

vinyl chloroacetate (2549-51-1) + 6-O-benzoylgalactal (58871-05-9,118396-88-6) → 6-O-benzoyl-3-O-chloroacetyl-galactal (118357-00-9,118396-89-7,126453-38-1)

Guidance literature:

With lipase from Pseudomonas fluorescens; In 1,2-dimethoxyethane; for 6h; Ambient temperature;

Reference yield:

vinyl benzoate (769-78-8,24991-32-0) → 6-O-benzoyl-3-O-chloroacetyl-glucal (118357-00-9,118396-89-7,126453-38-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / Lipase from Candida cylindracea (Lipase AY-20) / tetrahydrofuran / 6 h / Ambient temperature

2: 82 percent / Lipase from Pseudomonas fluorescens / 1,2-dimethoxy-ethane / 2 h / Ambient temperature

With lipase from Pseudomonas fluorescens; Lipase from Candida cylindracea (Lipase AY-20); In tetrahydrofuran; 1,2-dimethoxyethane;

upstream raw materials:

vinyl benzoate

vinyl chloroacetate

6-O-Benzoyl-D-glucal

6-O-benzoylgalactal

Refernces

• 1、 Holla, E. Wolfgang. "Enzymatische Synthesen selektiv geschuetzter Glycale". . p. 222 - 223. Retrieved 2007/10/02.