4-Thiazolecarboxylic acid, 5-methyl-2-phenyl-, ethyl ester

Base Information Edit

Chemical Name:4-Thiazolecarboxylic acid, 5-methyl-2-phenyl-, ethyl ester
CAS No.:132089-40-8
Molecular Formula:C13H13NO2S
Molecular Weight:247.31300
Hs Code.:
Mol file:132089-40-8.mol

Synonyms:2-POhenyl-4-methyl-5-ethoxycarbonylthiazol;5-methyl-2-phenyl-thiazole-4-carboxylic acid ethyl ester;5-methyl-2-phenylthiazole-4-carboxylic acid ethyl ester;ethyl 5-methyl-2-phenyl-1,3-thiazole-4-carboxylate;

Suppliers and Price of 4-Thiazolecarboxylic acid, 5-methyl-2-phenyl-, ethyl ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-Methyl-2-phenylthiazole-4-carboxylic acid ethyl ester 95%+
1g
$ 580.00

Labseeker
ethyl5-methyl-2-phenylthiazole-4-carboxylate 95
10g
$ 3938.00

Total 8 raw suppliers

Chemical Property of 4-Thiazolecarboxylic acid, 5-methyl-2-phenyl-, ethyl ester Edit

Chemical Property:

Melting Point:80-81 °C(Solv: ethyl acetate (141-78-6); ligroine (8032-32-4))
Boiling Point:372.9±34.0 °C(Predicted)
PSA：67.43000
Density:1.188±0.06 g/cm3(Predicted)
LogP:3.29520

Purity/Quality:

99% ^*data from raw suppliers

5-Methyl-2-phenylthiazole-4-carboxylic acid ethyl ester 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Thiazolecarboxylic acid, 5-methyl-2-phenyl-, ethyl ester

There total 4 articles about 4-Thiazolecarboxylic acid, 5-methyl-2-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 57332-84-0
3-bromo-2-oxo-butyric acid ethyl ester

: 2227-79-4
benzenecarbothioamide

: 132089-40-8
ethyl 5-methyl-2-phenylthiazole-4-carboxylate

Guidance literature:: In ethanol; for 12h; Heating;

Reference yield:

: 2009-97-4
ethyl 2-diazo-3-oxobutanoate

: 132089-40-8
ethyl 5-methyl-2-phenylthiazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / Rh₂(OAc)4 / 1,2-dichloro-ethane / Heating

2: 53 percent / Lawesson's reagent / tetrahydrofuran / Heating

With Lawessons reagent; dirhodium tetraacetate; In tetrahydrofuran; 1,2-dichloro-ethane;
DOI:10.1016/j.tet.2004.03.037

Reference yield:

: 141-97-9
ethyl acetoacetate

: 132089-40-8
ethyl 5-methyl-2-phenylthiazole-4-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / 4-acetamidobenzenesulfonyl azide; triethylamine / acetonitrile / 16 h / 20 °C

2: 62 percent / Rh₂(OAc)4 / 1,2-dichloro-ethane / Heating

3: 53 percent / Lawesson's reagent / tetrahydrofuran / Heating

With Lawessons reagent; 4-acetamidobenzenesulfonyl azide; triethylamine; dirhodium tetraacetate; In tetrahydrofuran; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1016/j.tet.2004.03.037