1-(2-methoxynaphthalen-1-yl)ethanone

Base Information

• Chemical Name: 1-(2-methoxynaphthalen-1-yl)ethanone
• CAS No.: 5672-94-6
• Molecular Formula: C13H12 O2
• Molecular Weight: 200.237
• Hs Code.: 2914500090
• Mol file: 5672-94-6.mol

Synonyms:1'-Acetonaphthone,2'-methoxy- (6CI,7CI,8CI); 1-(2-Methoxy-1-naphthalenyl)ethanone;1-Acetyl-2-methoxynaphthalene; 2-Methoxy-1-acetonaphthone

Chemical Property of 1-(2-methoxynaphthalen-1-yl)ethanone

Chemical Property:

• Vapor Pressure: 8.72E-05mmHg at 25°C
• Melting Point: 58 °C
• Boiling Point: 340.2°C at 760 mmHg
• Flash Point: 156.7°C
• PSA: 129.29000
• Density: 1.118g/cm³
• LogP: 5.93060
• Solubility.: soluble in Toluene

Purity/Quality:

99% ^*data from raw suppliers

2'-Methoxy-1'-acetonaphthone >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2-methoxynaphthalen-1-yl)ethanone

There total 6 articles about 1-(2-methoxynaphthalen-1-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-Methoxynaphthalene (93-04-9) + acetic anhydride (108-24-7) → 6-methoxy-2-acetylnaphthalene (3900-45-6) + 1-acetyl-2-methoxynaphthalene (5672-94-6)

Guidance literature:

With antimony(III) trifluoromethanesulfonate; lithium perchlorate; In nitromethane; at 50 ℃; for 5h;

DOI:10.1016/S0040-4020(00)00610-4

Reference yield: 51.0%

2-Methoxynaphthalene (93-04-9) + acetyl chloride (75-36-5) → 6-methoxy-2-acetylnaphthalene (3900-45-6) + 1-acetyl-2-methoxynaphthalene (5672-94-6)

Guidance literature:

acetyl chloride; With aluminum (III) chloride; In 1,2-dichloro-ethane; at 0 ℃; for 0.75h; Inert atmosphere;

2-Methoxynaphthalene; In 1,2-dichloro-ethane; at 0 ℃; for 4h; Inert atmosphere;

DOI:10.1016/j.tet.2016.02.001

Reference yield:

2-Methoxynaphthalene (93-04-9) + acetic anhydride (108-24-7) → 6-methoxy-2-acetylnaphthalene (3900-45-6) + 1-acetyl-2-methoxynaphthalene (5672-94-6) + 1-(7-methoxy-1-naphthalenyl)ethanone (3453-55-2)

Guidance literature:

With indium(III) chloride; In 1,2-dichloro-ethane; at 50 ℃; for 3h; Yield given. Yields of byproduct given;

upstream raw materials:

2-Methoxynaphthalene

acetic anhydride

acetyl chloride

aluminium trichloride

Downstream raw materials:

1-(2-Methoxy-<1>naphthyl)-3-(2-methoxy-phenyl)-prop-2-enon

Refernces

• 1、 Yamazaki, Tomoyoshi,Makihara, Makoto,Komura, Kenichi. "Zeolite catalyzed highly selective synthesis of 2-methoxy-6-acetylnaphthalene by Friedel-Crafts acylation of 2-methoxynaphthalene in acetic acid reaction media". . p. 170 - 176. Retrieved 2016/12/09.
• 2、 Serrano,Escola,Sanz,Garcia,Peral,Moreno,Linares. "Hierarchical ZSM-5 zeolite with uniform mesopores and improved catalytic properties". . p. 4206 - 4216. Retrieved 2016/06/09.