H-D-Ser-Obzl Hydrochloride salt

Base Information

• Chemical Name: H-D-Ser-Obzl Hydrochloride salt
• CAS No.: 133099-79-3
• Molecular Formula: C10H13NO3
• Molecular Weight: 195.218
• Mol file: 133099-79-3.mol

Synonyms:O-benzyl-D-serine;H-D-SER-OBZL;D-Serine, phenylmethyl ester;D-Ser-OBzl;D-Serin-benzylester;D-serine benzylester;(R)-2-Amino-3-hydroxy-propionic acid benzyl ester;D-Ser-OBn;

Chemical Property of H-D-Ser-Obzl Hydrochloride salt

Chemical Property:

• PSA: 72.55000
• LogP: 0.74970

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-D-Ser-Obzl Hydrochloride salt

There total 3 articles about H-D-Ser-Obzl Hydrochloride salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-Serine (312-84-5,83245-15-2) + benzyl alcohol (100-51-6,185532-71-2) → D-serine benzyl ester (133099-79-3)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; Reflux;

DOI:10.1021/acs.orglett.5b00512

Reference yield:

benzyl α-amino-β-hydroxypropionate (1738-71-2) → D-serine benzyl ester (133099-79-3)

Guidance literature:

With L-(-)-O,O'-dibenzoyltartaric acid;

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) → D-serine benzyl ester (133099-79-3)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl

2: O²,O³-dibenzoyl-L_g-tartaric acid

With hydrogenchloride; L-(-)-O,O'-dibenzoyltartaric acid;

upstream raw materials:

benzyl α-amino-β-hydroxypropionate

benzyl alcohol

D-Serine

Downstream raw materials:

D-Serine

(R)-benzyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate

N-[(3R)-15-methyl-3-(13-methyltetradecanoyloxy)hexadecanoyl]-D-serine benzyl ester

N-[(3S)-15-methyl-3-(13-methyltetradecanoyloxy)hexadecanoyl]-D-serine benzyl ester

Refernces