FmocGlu(OtBu)NH(CH₂)5NHZ

Base Information

• Chemical Name: FmocGlu(OtBu)NH(CH₂)5NHZ
• CAS No.: 1228766-32-2
• Molecular Formula: C₃₇H₄₅N₃O₇
• Molecular Weight: 643.78
• Mol file: 1228766-32-2.mol

Synonyms:

Chemical Property of FmocGlu(OtBu)NH(CH₂)5NHZ

Chemical Property:

Purity/Quality:

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Technology Process of FmocGlu(OtBu)NH(CH₂)5NHZ

There total 1 articles about FmocGlu(OtBu)NH(CH₂)5NHZ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

(5-aminopentyl)carbamic acid benzyl ester (69747-36-0) + Nα-Fmoc-Glu-(O-tBu)-OPfp (86061-04-3,200616-21-3) → FmocGlu(OtBu)NH(CH2)5NHZ (1228766-32-2)

Guidance literature:

With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1007/s00726-009-0337-5

Reference yield:

FmocGlu(OtBu)NH(CH2)5NHZ (1228766-32-2) → C33H37N3O7 (1228766-36-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1007/s00726-009-0337-5

upstream raw materials:

(5-aminopentyl)carbamic acid benzyl ester

N^α-Fmoc-Glu-(O-tBu)-OPfp

Downstream raw materials:

C₃₃H₃₇N₃O₇

Refernces