7-[[2-(Furan-2-yl)-2-methoxyiminoacetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Base Information Edit

Chemical Name:7-[[2-(Furan-2-yl)-2-methoxyiminoacetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS No.:56271-94-4
Molecular Formula:C15H15 N3 O7 S
Molecular Weight:381.366
Hs Code.:
European Community (EC) Number:260-086-2
Mol file:56271-94-4.mol

Synonyms:56271-94-4;PD164098;FT-0665941

Suppliers and Price of 7-[[2-(Furan-2-yl)-2-methoxyiminoacetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DescarbamoylCefuroxime
5mg
$ 175.00

Biosynth Carbosynth
Descarbamoyl cefuroxime
10 mg
$ 462.50

Biosynth Carbosynth
Descarbamoyl cefuroxime
5 mg
$ 254.40

Biosynth Carbosynth
Descarbamoyl cefuroxime
2 mg
$ 139.90

Biosynth Carbosynth
Descarbamoyl cefuroxime
50 mg
$ 1529.00

Biosynth Carbosynth
Descarbamoyl cefuroxime
25 mg
$ 841.00

American Custom Chemicals Corporation
DESCARBAMOYL CEFUROXIME 95.00%
5MG
$ 501.68

Total 22 raw suppliers

Chemical Property of 7-[[2-(Furan-2-yl)-2-methoxyiminoacetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Edit

Chemical Property:

Vapor Pressure:3Pa at 20℃
PKA:2.75±0.50(Predicted)
PSA：170.46000
Density:1.71±0.1 g/cm3(Predicted)
LogP:0.13920
Storage Temp.:-20°C Freezer, Under Inert Atmosphere
Water Solubility.:1mg/L
XLogP3:-0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:6
Exact Mass:381.06307100
Heavy Atom Count:26
Complexity:693

Purity/Quality:

99.9% ^*data from raw suppliers

DescarbamoylCefuroxime ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)CO)C(=O)O
Uses Descarbamoyl Cefuroxime (Cefuroxime Sodium EP Impurity A) is a degradation product of Cefuroxime, and an intermediate for the synthesis of Cephalosporin antibiotics A degradation product of Cefuroxime, and an intermediate for the synthesis of Cephalosporin antibiotics

Technology Process of 7-[[2-(Furan-2-yl)-2-methoxyiminoacetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

There total 12 articles about 7-[[2-(Furan-2-yl)-2-methoxyiminoacetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.1%

: 97148-39-5
(Z)-2-methoxyimino-2-(furyl-2-yl)acetic acid ammonium salt

: 15690-38-7
(6R,7R)-7-amino-3-hydroxymethyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

: 56271-94-4
(6R,7R)-7-[2-(2-furyl)-2-(methoxyimino)acetamido]-3-hydroxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Guidance literature:: (Z)-2-methoxyimino-2-(furyl-2-yl)acetic acid ammonium salt; With N,N-dimethyl acetamide; phosphorus pentachloride; In dichloromethane; at -30 - -10 ℃; for 1.33333h;

(6R,7R)-7-amino-3-hydroxymethyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; With sodium hydroxide; In dichloromethane; water; for 2h; pH=6.5 - 7;

Reference yield: 80.6%

: 57847-71-9
sodium 3-debenzoyl-acetyl-cefuroxime

: 56271-94-4
(6R,7R)-7-[2-(2-furyl)-2-(methoxyimino)acetamido]-3-hydroxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Guidance literature:: With hydrogenchloride; ethylenediaminetetraacetic acid; acetic acid; sodium hydroxide; In methanol; dichloromethane; water; at -20 - 5 ℃; for 1h; pH=2 - 6;