<α-2H>benzyl methyl sulfone

Base Information

• Chemical Name: <α-2H>benzyl methyl sulfone
• CAS No.: 344295-54-1
• Molecular Formula: C₈H₁₀O₂S
• Molecular Weight: 171.224
• Mol file: 344295-54-1.mol

Synonyms:

Chemical Property of <α-2H>benzyl methyl sulfone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <α-2H>benzyl methyl sulfone

There total 3 articles about <α-2H>benzyl methyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

<α-2H>benzyl methyl thioether (344246-80-6) → <α-2H>benzyl methyl sulfone (344295-54-1)

Guidance literature:

With dihydrogen peroxide; acetic acid; at 20 ℃; for 24h;

DOI:10.1021/jo00136a014

Reference yield:

C8H9(2)HOS (29293-45-6,29293-46-7,38238-99-2,38239-00-8,54352-85-1,99395-93-4,107438-78-8) → <α-2H>benzyl methyl sulfone (344295-54-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1021/jo00384a006

Reference yield:

S-(-)-benzylmethylsulfoxide (14090-81-4) → <α-2H>benzyl methyl sulfone (344295-54-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 45.2 percent / n-BuLi, D₂O / tetrahydrofuran; hexane / 1 h / -78 °C

2: m-chloroperbenzoic acid / CH₂Cl₂

With n-butyllithium; water-d2; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1021/jo00384a006

upstream raw materials:

<α-2H>benzyl methyl thioether

C₈H₉⁽²⁾HOS

S-(-)-benzylmethylsulfoxide

Refernces

• 1、 Biellmann, Jean-Francois,d'Orchymont, Hugues. "Preparation of Chiral 1-Deuteriobenzenemethanethiols by Using α',β Elimination of Carbanions Derived from Benzylic Thioethers". . p. 2882 - 2886. Retrieved 2007/10/02.