Ethyl 2-(4-chlorophenoxy)acetimidate hydrochloride

Base Information

• Chemical Name: Ethyl 2-(4-chlorophenoxy)acetimidate hydrochloride
• CAS No.: 3598-08-1
• Molecular Formula: C₁₀H₁₂ClNO₂*ClH
• Molecular Weight: 250.125
• Mol file: 3598-08-1.mol

Synonyms:

Chemical Property of Ethyl 2-(4-chlorophenoxy)acetimidate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl 2-(4-chlorophenoxy)acetimidate hydrochloride

There total 2 articles about Ethyl 2-(4-chlorophenoxy)acetimidate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + (4-chlorophenoxy)acetonitrile (3598-13-8) → Ethyl 2-(4-chlorophenoxy)acetimidate hydrochloride (3598-08-1)

Guidance literature:

With hydrogenchloride;

DOI:10.1016/S0040-4039(00)98575-7

Reference yield:

→ Ethyl 2-(4-chlorophenoxy)acetimidate hydrochloride (3598-08-1)

Guidance literature:

Reference yield:

trans-N-(4-aminocyclohexyl)-2-(4-chlorophenoxy)acetamide 2,2,2-trifluoroacetate + Ethyl 2-(4-chlorophenoxy)acetimidate hydrochloride (3598-08-1) → C2H4O2*C22H25Cl2N3O3

Guidance literature:

trans-N-(4-aminocyclohexyl)-2-(4-chlorophenoxy)acetamide 2,2,2-trifluoroacetate; Ethyl 2-(4-chlorophenoxy)acetimidate hydrochloride; With N-ethyl-N,N-diisopropylamine; In ethanol; at 20 ℃; for 24h;

Silicycle Si-TMA acetate resin; In methanol; at 20 ℃;

DOI:10.1002/cmdc.201500483

upstream raw materials:

ethanol

(4-chlorophenoxy)acetonitrile

Downstream raw materials:

(4-Chlor-phenoxy)-orthoessigsaeure-triaethylester

2-(4-chlorophenoxy)acetamide

2-(4-chloro-phenoxy)-acetamidine; hydrochloride

1-Chloro-4-((E)-2-chloro-vinyloxy)-benzene

Refernces

• 1、 -. "NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF". Page/Page column 37. . Retrieved 2010/11/03.