C₁₈H₁₅BrClN

Base Information

• Chemical Name: C₁₈H₁₅BrClN
• CAS No.: 1314253-72-9
• Molecular Formula: C₁₈H₁₅BrClN
• Molecular Weight: 360.681
• Mol file: 1314253-72-9.mol

Synonyms:

Chemical Property of C₁₈H₁₅BrClN

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₁₅BrClN

There total 3 articles about C₁₈H₁₅BrClN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H11BrClNO2 (1314253-43-4) → C18H15BrClN (1314253-72-9)

Guidance literature:

With sodium tetrahydroborate; In isopropyl alcohol; for 10h; Reflux;

DOI:10.1021/jm200543y

Reference yield:

(1-benzenesulfonyl-1H-pyrrol-3-yl)-(4-chlorophenyl)methanone (97188-31-3) → C18H15BrClN (1314253-72-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydroxide / 1,4-dioxane / 20 h / 25 °C

2.1: aluminum (III) chloride / 1,2-dichloro-ethane / 0.17 h / 25 °C / Inert atmosphere

2.2: 2 h / 25 °C / Inert atmosphere

3.1: sodium tetrahydroborate / isopropyl alcohol / 10 h / Reflux

With aluminum (III) chloride; sodium tetrahydroborate; sodium hydroxide; In 1,4-dioxane; 1,2-dichloro-ethane; isopropyl alcohol;

DOI:10.1021/jm200543y

Reference yield:

(4-chlorophenyl)-(1H-pyrrol-3-yl)methanone (62128-38-5) + 4-chlorobenzoyl chloride (586-75-4) → C18H15BrClN (1314253-72-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: aluminum (III) chloride / 1,2-dichloro-ethane / 0.17 h / 25 °C / Inert atmosphere

1.2: 2 h / 25 °C / Inert atmosphere

2.1: sodium tetrahydroborate / isopropyl alcohol / 10 h / Reflux

With aluminum (III) chloride; sodium tetrahydroborate; In 1,2-dichloro-ethane; isopropyl alcohol;

DOI:10.1021/jm200543y

upstream raw materials:

C₁₈H₁₁BrClNO₂

(4-chlorophenyl)-(1H-pyrrol-3-yl)methanone

4-chlorobenzoyl chloride

(1-benzenesulfonyl-1H-pyrrol-3-yl)-(4-chlorophenyl)methanone

Refernces