3,5-Dibromo-2-methoxybenzaldehyde

Base Information

• Chemical Name: 3,5-Dibromo-2-methoxybenzaldehyde
• CAS No.: 61657-65-6
• Molecular Formula: C8H6 Br2 O2
• Molecular Weight: 293.942
• Hs Code.: 2913000090
• DSSTox Substance ID: DTXSID40363469
• Wikidata: Q82147175
• Mol file: 61657-65-6.mol

Synonyms:3,5-Dibromo-2-methoxybenzaldehyde;61657-65-6;SCHEMBL1071145;DTXSID40363469;3,5-dibromo-2-methoxy-benzaldehyde;BBL009385;MFCD02093682;STK198768;AKOS000290638;3,5-Dibromo-2-methoxybenzaldehyde, 97%;VS-02060;CS-0116920;FT-0640771;EN300-08964;F82642;A833351;Z55992887

Chemical Property of 3,5-Dibromo-2-methoxybenzaldehyde

Chemical Property:

• Vapor Pressure: 0.000163mmHg at 25°C
• Melting Point: 93-96oC(lit.)
• Boiling Point: 330.8°C at 760 mmHg
• Flash Point: 153.9°C
• PSA: 26.30000
• Density: 1.866g/cm³
• LogP: 3.03270
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 293.87141
• Heavy Atom Count: 12
• Complexity: 163

Purity/Quality:

98%Min ^*data from raw suppliers

3,5-Dibromo-2-methoxybenzaldehyde 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1Br)Br)C=O

Technology Process of 3,5-Dibromo-2-methoxybenzaldehyde

There total 5 articles about 3,5-Dibromo-2-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3,5-Dibromosalicylaldehyde (90-59-5) + dimethyl sulfate (77-78-1) → 3,5-dibromo-2-methoxybenzaldehyde (61657-65-6)

Guidance literature:

With potassium carbonate;

DOI:10.1007/BF02494298

Reference yield: 65.0%

3,5-Dibromosalicylaldehyde (90-59-5) + methyl iodide (74-88-4) → 3,5-dibromo-2-methoxybenzaldehyde (61657-65-6)

Guidance literature:

3,5-Dibromosalicylaldehyde; With potassium carbonate; In DMF (N,N-dimethyl-formamide); for 0.5h;

methyl iodide; In DMF (N,N-dimethyl-formamide); at 0 ℃; for 1h;

In DMF (N,N-dimethyl-formamide); at 20 ℃; for 14h;

Reference yield:

methyl bromide (74-83-9) + 3,5-Dibromosalicylaldehyde (90-59-5) → 3,5-dibromo-2-methoxybenzaldehyde (61657-65-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃;

DOI:10.1016/j.bmcl.2017.04.048

upstream raw materials:

3,5-Dibromosalicylaldehyde

dimethyl sulfate

salicylaldehyde

methyl iodide

Downstream raw materials:

3-(3',5'-Dibromo-2'-methoxyphenyl)-2-formamido-2-propenoic Acid Methyl Ester

3-(3',5'-Dibromo-2'-methoxyphenyl)-1H-pyrrole-2,4-dicarboxylic Acid Dimethyl Ester

N-[2-methoxy-3,5-bis(3-methoxypropyl)benzyl]cyclopropanamine

2-methoxy-3,5-bis(3-methoxypropyl)benzaldehyde

Refernces

• 1、 -. "NITROGENOUS CYCLIC KETONE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE". Page 71-72. . Retrieved 2010/02/08.