C₂₃H₁₆O₆

Base Information

• Chemical Name: C₂₃H₁₆O₆
• CAS No.: 1393549-95-5
• Molecular Formula: C₂₃H₁₆O₆
• Molecular Weight: 388.376
• Mol file: 1393549-95-5.mol

Synonyms:

Chemical Property of C₂₃H₁₆O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₁₆O₆

There total 7 articles about C₂₃H₁₆O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

2-benzoyl-4H,9H-naphtho[2,3-b]furan-4,9-dione (676158-78-4) + acetic anhydride (108-24-7) → C23H16O6 (1393549-95-5)

Guidance literature:

With pyridine; zinc; at 20 ℃;

DOI:10.1021/jm3009597

Reference yield:

2-methylnaphtho[2,3-b]furan-4,9-dione (4512-56-5) → C23H16O6 (1393549-95-5)

Guidance literature:

Multi-step reaction with 7 steps

1.1: selenium(IV) oxide; silica gel / dichloromethane / Microwave irradiation

2.1: acetic acid; dihydrogen peroxide / 1 h / 75 °C

3.1: quinoline; copper chromite / 2 h / Reflux

4.1: tetrabutylammomium bromide; potassium hydroxide; sodium dithionite / tetrahydrofuran / Inert atmosphere

5.1: n-butyllithium / tetrahydrofuran / -15 °C / Inert atmosphere

5.2: 20 °C / Inert atmosphere

6.1: water / acetonitrile / 0.33 h / 0 °C

6.2: 0.33 h

7.1: pyridine; zinc / 20 °C

With pyridine; quinoline; selenium(IV) oxide; n-butyllithium; sodium dithionite; copper chromite; tetrabutylammomium bromide; water; dihydrogen peroxide; silica gel; acetic acid; potassium hydroxide; zinc; In tetrahydrofuran; dichloromethane; acetonitrile;

DOI:10.1021/jm3009597

Reference yield:

naphtho[2,3-b]furan-4,9-dione (5656-82-6) → C23H16O6 (1393549-95-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrabutylammomium bromide; potassium hydroxide; sodium dithionite / tetrahydrofuran / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / -15 °C / Inert atmosphere

2.2: 20 °C / Inert atmosphere

3.1: water / acetonitrile / 0.33 h / 0 °C

3.2: 0.33 h

4.1: pyridine; zinc / 20 °C

With pyridine; n-butyllithium; sodium dithionite; tetrabutylammomium bromide; water; potassium hydroxide; zinc; In tetrahydrofuran; acetonitrile;

DOI:10.1021/jm3009597

upstream raw materials:

C₂₁H₁₆O₄

2-benzoyl-4H,9H-naphtho[2,3-b]furan-4,9-dione

acetic anhydride

4,9-dioxo-4,9-dihydronaphtho[2,3-b]furan-2-carbaldehyde

Refernces