4-bromo-2-hydroxyphenyl dimethylcarbamate

Base Information

• Chemical Name: 4-bromo-2-hydroxyphenyl dimethylcarbamate
• CAS No.: 1631050-36-6
• Molecular Formula: C₉H₁₀BrNO₃
• Molecular Weight: 260.087
• Mol file: 1631050-36-6.mol

Synonyms:

Chemical Property of 4-bromo-2-hydroxyphenyl dimethylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-bromo-2-hydroxyphenyl dimethylcarbamate

There total 2 articles about 4-bromo-2-hydroxyphenyl dimethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

4-bromophenyl dimethylcarbamate (7308-55-6) → 4-bromo-2-hydroxyphenyl dimethylcarbamate (1631050-36-6)

Guidance literature:

With dipotassium peroxodisulfate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; trifluoroacetic acid; trifluoroacetic anhydride; at 80 ℃; for 2.5h; regioselective reaction; Sealed tube;

DOI:10.1002/adsc.201300999

Reference yield:

4-bromo-phenol (106-41-2) → 4-bromo-2-hydroxyphenyl dimethylcarbamate (1631050-36-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / Sealed tube; Reflux

2: [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; trifluoroacetic acid; dipotassium peroxodisulfate; trifluoroacetic anhydride / 2.5 h / 80 °C / Sealed tube

With dipotassium peroxodisulfate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; potassium carbonate; trifluoroacetic acid; trifluoroacetic anhydride; In acetonitrile;

DOI:10.1002/adsc.201300999

upstream raw materials:

4-bromophenyl dimethylcarbamate

4-bromo-phenol

Refernces