C₁₇H₂₀N₂O₂

Base Information

• Chemical Name: C₁₇H₂₀N₂O₂
• CAS No.: 477807-98-0
• Molecular Formula: C₁₇H₂₀N₂O₂
• Molecular Weight: 284.358
• Mol file: 477807-98-0.mol

Synonyms:

Chemical Property of C₁₇H₂₀N₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₂₀N₂O₂

There total 4 articles about C₁₇H₂₀N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1R,2S)-2-Phenethylamino-1-phenyl-propan-1-ol (220999-88-2) → C17H20N2O2 (477807-98-0)

Guidance literature:

With hydrogenchloride; sodium nitrite; In tetrahydrofuran; water; for 24h;

DOI:10.1002/jhet.5570390431

Reference yield:

(1R,2S)-norephedrine (492-41-1,58550-13-3,757124-50-8) → C17H20N2O2 (477807-98-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 84 percent / NaOH / CH₂Cl₂; H₂O / 16 h

2: 87 percent / NaBH₄; iodine / tetrahydrofuran / 15 h / Heating

3: sodium nitrite; HCl / tetrahydrofuran; H₂O / 24 h

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; iodine; sodium nitrite; In tetrahydrofuran; dichloromethane; water;

DOI:10.1002/jhet.5570390431

Reference yield:

phenylacetic acid-((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethylamide) (477807-90-2) → C17H20N2O2 (477807-98-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / NaBH₄; iodine / tetrahydrofuran / 15 h / Heating

2: sodium nitrite; HCl / tetrahydrofuran; H₂O / 24 h

With hydrogenchloride; sodium tetrahydroborate; iodine; sodium nitrite; In tetrahydrofuran; water;

DOI:10.1002/jhet.5570390431

upstream raw materials:

(1R,2S)-2-Phenethylamino-1-phenyl-propan-1-ol

(1R,2S)-norephedrine

phenylacetic acid-((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethylamide)

phenylacetyl chloride

Refernces