anti-3-hydroxy-1-adamantyl-amphi-glyoxime dibenzoate

Base Information

• Chemical Name: anti-3-hydroxy-1-adamantyl-amphi-glyoxime dibenzoate
• CAS No.: 110574-51-1
• Molecular Formula: C₂₆H₂₆N₂O₅
• Molecular Weight: 446.503
• Mol file: 110574-51-1.mol

Synonyms:

Chemical Property of anti-3-hydroxy-1-adamantyl-amphi-glyoxime dibenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of anti-3-hydroxy-1-adamantyl-amphi-glyoxime dibenzoate

There total 4 articles about anti-3-hydroxy-1-adamantyl-amphi-glyoxime dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

anti-<1-(3-hydroxy-adamantyl)>-amphi-glyoxime (110574-45-3) + benzoyl chloride (98-88-4) → anti-3-hydroxy-1-adamantyl-amphi-glyoxime dibenzoate (110574-51-1)

Guidance literature:

With pyridine; In benzene; for 1h; Ambient temperature;

Reference yield:

α-Bromomethyl 3-nitroxy-1-adamantyl ketonme (69752-09-6) → anti-3-hydroxy-1-adamantyl-amphi-glyoxime dibenzoate (110574-51-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / NH₂OH_.HCl, NaOH / ethanol / Heating

2: 60 percent / pyridine / benzene / 1 h / Ambient temperature

With pyridine; sodium hydroxide; hydroxylamine hydrochloride; In ethanol; benzene;

Reference yield:

3-nitroxyadamantane-1-carboxylic acid (50795-82-9) → anti-3-hydroxy-1-adamantyl-amphi-glyoxime dibenzoate (110574-51-1)

Guidance literature:

Multi-step reaction with 4 steps

1: SOCl₂ / 1.5 h / 35 - 36 °C

2: 2) HBr

3: 60 percent / NH₂OH_.HCl, NaOH / ethanol / Heating

4: 60 percent / pyridine / benzene / 1 h / Ambient temperature

With pyridine; sodium hydroxide; thionyl chloride; hydroxylamine hydrochloride; hydrogen bromide; In ethanol; benzene;

upstream raw materials:

anti-<1-(3-hydroxy-adamantyl)>-amphi-glyoxime

benzoyl chloride

α-Bromomethyl 3-nitroxy-1-adamantyl ketonme

3-nitroxyadamantane-1-carboxylic acid

Refernces