ephedrine hydrazine

Base Information

• Chemical Name: ephedrine hydrazine
• CAS No.: 91010-58-1
• Molecular Formula: C₁₀H₁₆N₂O
• Molecular Weight: 180.25
• Mol file: 91010-58-1.mol

Synonyms:

Chemical Property of ephedrine hydrazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ephedrine hydrazine

There total 1 articles about ephedrine hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ ephedrine hydrazine (91010-58-1)

Guidance literature:

trans-4,5-Dimethyl-6-phenyl-2-(2-methoxy-phenyl)-5,6-dihydro-4H-1,3,4-oxadiazin, konz. H2SO4/W. (1:2 Vol.) <1/2 d Raumtemp.; 1h 70grad>;

DOI:10.1021/jo01026a035

Reference yield: 74.0%

ephedrine hydrazine (91010-58-1) + Diethyl carbonate (105-58-8,76619-83-5) → 3,4,5,6-tetrahydro-4,5-dimethyl-6-phenyl-2H-1,3,4-oxadiazin-2-one (16639-23-9,16638-85-0)

Guidance literature:

With lithium hydride; In hexane; for 24h; Heating;

DOI:10.1081/SCC-120028356

Reference yield:

ephedrine hydrazine (91010-58-1) → 2-(1,1-dimethyl-butyl)-4,5r-dimethyl-6t-phenyl-5,6-dihydro-4H-[1,3,4]oxadiazine

Guidance literature:

Multi-step reaction with 2 steps

1: Py

2: H₂SO₄

With pyridine; sulfuric acid;

DOI:10.1021/jo01026a036

Downstream raw materials:

2,2-dimethyl-pentanoic acid N'-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N'-methyl-hydrazide

2,2-dimethyl-propionic acid N'-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N'-methyl-hydrazide

3,4,5,6-tetrahydro-4,5-dimethyl-6-phenyl-2H-1,3,4-oxadiazin-2-one

2-tert-butyl-4,5r-dimethyl-6t-phenyl-5,6-dihydro-4H-[1,3,4]oxadiazine