N-(sulfonatooxy)-N-acetyl-4-aminostilbene

Base Information

• Chemical Name: N-(sulfonatooxy)-N-acetyl-4-aminostilbene
• CAS No.: 211029-25-3
• Molecular Formula: C₁₆H₁₄NO₅S
• Molecular Weight: 332.357
• Mol file: 211029-25-3.mol

Synonyms:

Chemical Property of N-(sulfonatooxy)-N-acetyl-4-aminostilbene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(sulfonatooxy)-N-acetyl-4-aminostilbene

There total 1 articles about N-(sulfonatooxy)-N-acetyl-4-aminostilbene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-hydroxy-N-acetyl-4-aminostilbene (843-23-2) → N-(sulfonatooxy)-N-acetyl-4-aminostilbene (211029-25-3)

Guidance literature:

With sulfuric acid; dicyclohexyl-carbodiimide;

DOI:10.1021/jo980500z

Reference yield: 40.0%

N-(sulfonatooxy)-N-acetyl-4-aminostilbene (211029-25-3) → 3-azido-N-acetyl-4-aminostilbene + N-[4-((1R,2R)-2-Azido-1-hydroxy-2-phenyl-ethyl)-phenyl]-acetamide + N-[4-((1R,2R)-1,2-Diazido-2-phenyl-ethyl)-phenyl]-acetamide + N-[4-((1R,2S)-1,2-Diazido-2-phenyl-ethyl)-phenyl]-acetamide

Guidance literature:

With sodium azide; In acetonitrile; Further byproducts given; phosphate buffer, pH 7.2;

DOI:10.1021/jo980500z

Reference yield: 12.4%

N-(sulfonatooxy)-N-acetyl-4-aminostilbene (211029-25-3) → 3-azido-N-acetyl-4-aminostilbene + N-[4-((1R,2R)-1,2-Dihydroxy-2-phenyl-ethyl)-phenyl]-acetamide (60239-58-9) + N-[4-((1R,2R)-2-Azido-1-hydroxy-2-phenyl-ethyl)-phenyl]-acetamide + N-[4-((1S,2R)-2-Azido-1-hydroxy-2-phenyl-ethyl)-phenyl]-acetamide + N-[4-((1R,2R)-1,2-Diazido-2-phenyl-ethyl)-phenyl]-acetamide + N-[4-((1R,2S)-1,2-Diazido-2-phenyl-ethyl)-phenyl]-acetamide

Guidance literature:

With sodium azide; water; In acetonitrile; at 20 ℃; Rate constant; Product distribution; phosphate buffer, pH 7.2, μ 0.5; hydrolysis in the presence and absence of NaN3; formation of electrophilic intermediates; trapping of intermediates by azide ion and H2O; trapping ratio;

DOI:10.1021/jo980500z

upstream raw materials:

N-hydroxy-N-acetyl-4-aminostilbene

Downstream raw materials:

N-[4-((1R,2R)-1,2-Dihydroxy-2-phenyl-ethyl)-phenyl]-acetamide

Refernces