trans-2-phenyl-1λ⁴,3-dithian-1-one

Base Information

• Chemical Name: trans-2-phenyl-1λ⁴,3-dithian-1-one
• CAS No.: 60349-76-0
• Molecular Formula: C₁₀H₁₂OS₂
• Molecular Weight: 212.337
• Mol file: 60349-76-0.mol

Synonyms:

Chemical Property of trans-2-phenyl-1λ⁴,3-dithian-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-2-phenyl-1λ⁴,3-dithian-1-one

There total 8 articles about trans-2-phenyl-1λ⁴,3-dithian-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-Phenyl-[1,3]dithiane (5425-44-5) → trans-2-phenyl-1λ4,3-dithian-1-one (60349-76-0,60349-79-3,93974-18-6,131309-64-3,134235-93-1)

Guidance literature:

With phthaloyl peroxide; In dichloromethane; at 25 ℃; for 8h; diastereoselective reaction; Schlenk technique;

DOI:10.1039/c7ob00021a

Reference yield: 94.0%

2-Phenyl-[1,3]dithiane (5425-44-5) → trans-(1R,2R)-2-phenyl-1,3-dithiane 1-oxide (60349-76-0,60349-79-3,93974-18-6,131309-64-3,134235-93-1)

Guidance literature:

With bis(acetylacetonate)oxovanadium; C₂₁H₃₅NO₂; dihydrogen peroxide; In dichloromethane; at 25 ℃; for 16h; optical yield given as %ee; enantioselective reaction;

DOI:10.1002/adsc.201000803

Reference yield:

2-Phenyl-[1,3]dithiane (5425-44-5) → trans-(1R,2R)-2-phenyl-1,3-dithiane 1-oxide (60349-76-0,60349-79-3,93974-18-6,131309-64-3,134235-93-1) + (+)-(1S,2S)-2-phenyl-1λ4,3-dithiane 1-oxide

Guidance literature:

With 2,4-bis(1,1-dimethylethyl)-6-({[(1S)-1-hydroxymethyl-2,2-dimethylpropyl]imino}methyl)phenol; water; dihydrogen peroxide; bis(acetylacetonate)oxovanadium; In dichloromethane; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1055/s-1998-1948

upstream raw materials:

2-acetyl-2-phenyl-1,3-dithiane

2-Phenyl-[1,3]dithiane

Downstream raw materials:

2-phenyl tetrahydro thiophene

Refernces

• 1、 Meninno, Sara,Parrella, Alessandro,Brancatelli, Giovanna,Geremia, Silvano,Gaeta, Carmine,Talotta, Carmen,Neri, Placido,Lattanzi, Alessandra. "Polyoxomolybdate-Calix[4]arene Hybrid: A Catalyst for Sulfoxidation Reactions with Hydrogen Peroxide". supporting information. p. 5100 - 5103. Retrieved 2015/11/03.
• 2、 Wu, Yinuo,Mao, Fei,Meng, Fanchao,Li, Xingshu. "Enantioselective vanadium-catalyzed oxidation of 1,3-dithianes from aldehydes and ketones using β-amino alcohol derived schiff base ligands". supporting information; experimental part. p. 1707 - 1712. Retrieved 2011/10/01.