3-chloro-4-methoxyphenyl benzoate

Base Information

• Chemical Name: 3-chloro-4-methoxyphenyl benzoate
• CAS No.: 100623-16-3
• Molecular Formula: C₁₄H₁₁ClO₃
• Molecular Weight: 262.693
• Mol file: 100623-16-3.mol

Synonyms:

Chemical Property of 3-chloro-4-methoxyphenyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-chloro-4-methoxyphenyl benzoate

There total 3 articles about 3-chloro-4-methoxyphenyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

2-chloro-4-fluoro-1-methoxy-benzene (2267-25-6) + benzoic acid (65-85-0,8013-63-6) → 3-chloro-4-methoxyphenyl benzoate (100623-16-3)

Guidance literature:

With 3,6‐di‐tert‐butyl‐9‐(2,6‐dimethylphenyl)‐10‐(4‐(trifluoromethyl)phenyl)acridin‐10‐iumtetrafluoroborate; sodium hydrogencarbonate; In 2,2,2-trifluoroethanol; at 45 - 50 ℃; for 18h; Irradiation; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.0c09296

Reference yield:

4-methoxyphenyl benzoate (1523-19-9) → 3-chloro-4-methoxyphenyl benzoate (100623-16-3)

Guidance literature:

With formic acid; chlorine;

Reference yield:

3-chloro-4-methoxyphenol (18093-12-4) + benzoyl chloride (98-88-4) → 3-chloro-4-methoxyphenyl benzoate (100623-16-3)

Guidance literature:

upstream raw materials:

4-methoxyphenyl benzoate

3-chloro-4-methoxyphenol

benzoyl chloride

2-chloro-4-fluoro-1-methoxy-benzene

Downstream raw materials:

3-chloro-4-methoxyphenol

Refernces