Technology Process of 6-(3-hydroxy-4-methoxyphenethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one
There total 7 articles about 6-(3-hydroxy-4-methoxyphenethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
5%-palladium/activated carbon; hydrogen;
In
tetrahydrofuran;
for 2h;
under 760.051 Torr;
DOI:10.1002/cmdc.202100727
- Guidance literature:
-
Multi-step reaction with 2 steps
1: acetone / 12 h / 20 °C
2: hydrogen; 5%-palladium/activated carbon / tetrahydrofuran / 2 h / 760.05 Torr
With
5%-palladium/activated carbon; hydrogen;
In
tetrahydrofuran; acetone;
DOI:10.1002/cmdc.202100727
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: n-butyllithium / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: selenium(IV) dioxide / 1,4-dioxane / 12 h / Reflux
3.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere
3.2: 0.5 h / 0 °C / Inert atmosphere
3.3: 12.5 h / -78 - 20 °C / Inert atmosphere
4.1: potassium carbonate; methanol / 6 h / 20 °C / Inert atmosphere
5.1: acetone / 12 h / 20 °C
6.1: hydrogen; 5%-palladium/activated carbon / tetrahydrofuran / 2 h / 760.05 Torr
With
methanol; selenium(IV) dioxide; n-butyllithium; 5%-palladium/activated carbon; hydrogen; sodium hydride; potassium carbonate;
In
tetrahydrofuran; 1,4-dioxane; acetone; mineral oil;
1.1: |Wittig Olefination / 1.2: |Wittig Olefination;
DOI:10.1002/cmdc.202100727