BBTPA

Base Information

• Chemical Name: BBTPA
• CAS No.: 1243278-16-1
• Molecular Formula: C₄₈H₄₂Br₂N₂
• Molecular Weight: 806.683
• Mol file: 1243278-16-1.mol

Synonyms:

Chemical Property of BBTPA

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BBTPA

There total 3 articles about BBTPA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1,4-bromoiodobenzene (589-87-7) + bis[4-(2-phenyl-2-isopropyl)phenyl]-4-aminophenylamine (1243278-14-9) → BBTPA (1243278-16-1)

Guidance literature:

With 1,1'-bis-(diphenylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; sodium t-butanolate; In toluene; for 10h; Reflux; Inert atmosphere;

DOI:10.1002/pola.24104

Reference yield:

bis[4-(2-phenyl-2-propyl)phenyl]amine (10081-67-1) → BBTPA (1243278-16-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydride / dimethyl sulfoxide / 48 h / 120 °C

2: palladium on activated charcoal; hydrazine hydrate / 12 h / Reflux; Inert atmosphere

3: 1,1'-bis-(diphenylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; sodium t-butanolate / toluene / 10 h / Reflux; Inert atmosphere

With 1,1'-bis-(diphenylphosphino)ferrocene; palladium on activated charcoal; sodium hydride; hydrazine hydrate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; sodium t-butanolate; In dimethyl sulfoxide; toluene; 3: Buchwald-Hartwig reaction;

DOI:10.1002/pola.24104

Reference yield:

4-Fluoronitrobenzene (350-46-9,178603-76-4) → BBTPA (1243278-16-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydride / dimethyl sulfoxide / 48 h / 120 °C

2: palladium on activated charcoal; hydrazine hydrate / 12 h / Reflux; Inert atmosphere

3: 1,1'-bis-(diphenylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; sodium t-butanolate / toluene / 10 h / Reflux; Inert atmosphere

With 1,1'-bis-(diphenylphosphino)ferrocene; palladium on activated charcoal; sodium hydride; hydrazine hydrate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; sodium t-butanolate; In dimethyl sulfoxide; toluene; 3: Buchwald-Hartwig reaction;

DOI:10.1002/pola.24104

upstream raw materials:

1,4-bromoiodobenzene

bis[4-(2-phenyl-2-isopropyl)phenyl]-4-aminophenylamine

bis[4-(2-phenyl-2-propyl)phenyl]amine

4-Fluoronitrobenzene

Refernces